GPBAR1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
GPBAR1
HGNC name
G protein-coupled bile acid receptor 1
Family
Bile acid receptor
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=37

Description

Figure. Concentration-dependent activation of GPBAR1 by TGR5 agonist. Reporter cells were transfected with the expression plasmid for G protein-coupled bile acid receptor 1 (GPBAR1) and treated with various concentrations of TGR5 agonist. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 350 nM.