CCR5

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
CCR5
HGNC name
C-C motif chemokine receptor 5
Family
Chemokine receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=62
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Description

Figure. Concentration-dependent activation of CCR5 by CCL4. Reporter cells were transfected with either the expression plasmid for C-C motif chemo­kine receptor 5 (CCR5) or the mock plasmid and treated with various concentrations of C-C motif chemo­kine ligand 4 (CCL4). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 7.1 nM.