Human CCR6

Figure. Concentration-dependent activation of CCR6 by CCL20

Reporter cells were transfected with either the expression plasmid for human C-C motif chemokine receptor 6 (CCR6) or the mock plasmid and treated with various concentrations of CCL20. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 3.8 nM.

Nomenclature
C-C motif chemokine receptor 6
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Immunology/Infection, Oncology, Hematology, Ophthalmology, Cardiology, Respiratory, Gastrointestinal, Dermatology, Musculoskeletal, Urology/Reproduction, Human non-orphan GPCRs

CCR6 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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