CX3CR1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
CX3CR1
HGNC name
C-X3-C motif chemokine receptor 1
Family
Chemokine receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=74
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Description

Figure. Concentration-dependent activation of CX3CR1 by CX3CL1. Reporter cells were transfected with either the expression plasmid for C-X3-C motif chemo­kine receptor 1 (CX3CR1) or the mock plasmid and treated with various concentrations of C-X3-C motif chemo­kine ligand 1 (CX3CL1). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 1.8 nM.