Human XCR1

Figure. Concentration-dependent activation of XCR1 by XCL1

Reporter cells were transfected with either the expression plasmid for human X-C motif chemokine receptor 1 (XCR1) or the mock plasmid and treated with various concentrations of XCL1. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 43 nM.