Figure. Concentration-dependent activation of CCKBR by CCK-8. Reporter cells were transfected with either the expression plasmid for chole­cysto­kinin B receptor (CCKBR) or the mock plasmid and treated with various concentrations of chole­cysto­kinin 8 (CCK-8). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 490 pM.