CRHR1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
CRHR1
HGNC name
corticotropin releasing hormone receptor 1
Family
Corticotropin-releasing factor receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=212
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Description

Figure. Concentration-dependent activation of CRHR1 by CRH. Reporter cells were transfected with either the expression plasmid for cortico­tropin re­leas­ing hormone receptor 1 (CRHR1) or the mock plasmid and treated with various concentrations of cortico­tropin re­leas­ing hormone (CRH). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 22 nM.