Human DRD4

Figure. Concentration-dependent activation of DRD4 by dopamine

Reporter cells were transfected with either the expression plasmid for human dopamine receptor D4 (DRD4) or the mock plasmid and treated with various concentrations of dopamine. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 260 nM.

Nomenclature
dopamine receptor D4
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Psychiatry, Neurology, Human non-orphan GPCRs

DRD4 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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