Human EDNRB

Figure. Concentration-dependent activation of EDNRB by ET‐1

Reporter cells were transfected with either the expression plasmid for human endothelin receptor type B (EDNRB) or the mock plasmid and treated with various concentrations of ET‐1. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 5.0 nM.

説明

Nomenclature: endothelin receptor type B
Available assay modes: Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels: à la carte, Immunology/Infection, Oncology, Hematology, Endocrinology/Metabolism, Neurology, Ophthalmology, Cardiology, Respiratory, Gastrointestinal, Dermatology, Musculoskeletal, Urology/Reproduction, Human non-orphan GPCRs

EDNRB orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors


Human	EDNRA endothelin receptor type A
Human	EDNRB endothelin receptor type B
Mouse	Ednra endothelin receptor type A
Mouse	Ednrb endothelin receptor type B

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