Human GABBR2

Figure. Concentration-dependent activation of GABBR1+GABBR2 by baclofen

Reporter cells were transfected with either the expression plasmid for human GABBR1+GABBR2 or the mock plasmid and treated with various concentrations of baclofen. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 9.4 µM.

Nomenclature
gamma-aminobutyric acid type B receptor subunit 2
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Psychiatry, Neurology, Musculoskeletal, Human non-orphan GPCRs

GABBR2 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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