Human GLP1R

Figure. Concentration-dependent activation of GLP1R by GLP1‐(7‐36)amide

Reporter cells were transfected with either the expression plasmid for human glucagon like peptide 1 receptor (GLP1R) or the mock plasmid and treated with various concentrations of GLP1‐(7‐36)amide. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 7.6 nM.

説明

Nomenclature: glucagon like peptide 1 receptor
Available assay modes: Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels: à la carte, Oncology, Hematology, Endocrinology/Metabolism, Ophthalmology, Cardiology, Gastrointestinal, Musculoskeletal, Urology/Reproduction, Human non-orphan GPCRs

GLP1R orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors


Human	GHRHR growth hormone releasing hormone receptor
Human	GIPR gastric inhibitory polypeptide receptor
Human	GLP1R glucagon like peptide 1 receptor
Human	GLP2R glucagon like peptide 2 receptor
Human	GCGR glucagon receptor
Human	SCTR secretin receptor
Mouse	Ghrhr growth hormone releasing hormone receptor
Mouse	Gipr gastric inhibitory polypeptide receptor
Mouse	Glp1r glucagon-like peptide 1 receptor
Mouse	Glp2r glucagon-like peptide 2 receptor
Mouse	Gcgr glucagon receptor

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