Human TSHR

Figure. Concentration-dependent activation of TSHR by TSH

Reporter cells were transfected with either the expression plasmid for human thyroid stimulating hormone receptor (TSHR) or the mock plasmid and treated with various concentrations of TSH. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 18 ng/ml.

Nomenclature
thyroid stimulating hormone receptor
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Immunology/Infection, Oncology, Endocrinology/Metabolism, Ophthalmology, Respiratory, Dermatology, Musculoskeletal, Urology/Reproduction, Human non-orphan GPCRs

TSHR orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors