Figure. Concentration-dependent activation of GNRHR by LH-RH. Reporter cells were transfected with the expression plasmid for gonad­o­tro­pin re­leas­ing hormone receptor (GNRHR) and treated with various concentrations of lu­te­in­iz­ing hormone-re­leas­ing hormone (LH-RH). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 93 pM.