Human HRH2

Figure. Concentration-dependent activation of HRH2 by histamine

Reporter cells were transfected with either the expression plasmid for human histamine receptor H2 (HRH2) or the mock plasmid and treated with various concentrations of histamine. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 240 nM.