HCAR2

Figure. Concentration-dependent activation of HCAR2 by nicotinic acid
Reporter cells were transfected with either the expression plasmid for hydroxycarboxylic acid receptor 2 (HCAR2) or the mock plasmid and treated with various concentrations of nicotinic acid. Data points shown are the mean ± SEM of an experiment, and the curve is a fit to Hill equation with an EC50 of 5.8 µM.
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
Ophthalmology, Dermatology, Non-orphan GPCRs
Symbol
HCAR2
Nomenclature
hydroxycarboxylic acid receptor 2
Family
Species
Human