CYSLTR1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
CYSLTR1
HGNC name
cysteinyl leukotriene receptor 1
Family
Leukotriene receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=269

Description

Figure. Concentration-dependent activation of CYSLTR1 by LTD4. Reporter cells were transfected with either the expression plasmid for cys­teinyl leuko­triene receptor 1 (CYSLTR1) or the mock plasmid and treated with various concentrations of leuko­triene D4 (LTD4). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 7.9 nM.