OXER1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
OXER1
HGNC name
oxoeicosanoid receptor 1
Family
Leukotriene receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=271
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Description

Figure. Concentration-dependent activation of OXER1 by 5-oxo-ETE. Reporter cells were transfected with either the expression plasmid for oxo­eicosa­noid receptor 1 (OXER1) or the mock plasmid and treated with various concentrations of 5-oxo-eicosa­tetra­enoic acid (5-oxo-ETE). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 130 nM.