Figure. Concentration-dependent activation of OXER1 by 5-oxo-ETE. Reporter cells were transfected with either the expression plasmid for oxo­eicosa­noid receptor 1 (OXER1) or the mock plasmid and treated with various concentrations of 5-oxo-eicosa­tetra­enoic acid (5-oxo-ETE). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 130 nM.