S1PR4

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
S1PR4
HGNC name
sphingosine-1-phosphate receptor 4
Family
Lysophospholipid (S1P) receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=278
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Description

Figure. Concentration-dependent activation of S1PR4 by S1P. Reporter cells were transfected with either the expression plasmid for sphin­go­sine-1-phos­phate receptor 4 (S1PR4) or the mock plasmid and treated with various concentrations of sphin­go­sine 1-phos­phate (S1P). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 7.3 nM.