MC5R

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
MC5R
HGNC name
melanocortin 5 receptor
Family
Melanocortin receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=286
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Description

Figure. Concentration-dependent activation of MC5R by α-MSH. Reporter cells were transfected with either the expression plasmid for melano­cortin 5 receptor (MC5R) or the mock plasmid and treated with various concentrations of α-melano­cyte-stim­u­lat­ing hormone (α-MSH). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 8.5 nM.