Description
Figure. Concentration-dependent activation of MC5R by α-MSH. Reporter cells were transfected with either the expression plasmid for melanocortin 5 receptor (MC5R) or the mock plasmid and treated with various concentrations of α-melanocyte-stimulating hormone (α-MSH). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 8.5 nM.