Human GPR174

Figure. Concentration-dependent activation of GPR174 by LPS

Reporter cells were transfected with either the expression plasmid for human G protein-coupled receptor 174 (GPR174) or the mock plasmid and treated with various concentrations of LPS. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 22 nM.

Nomenclature
G protein-coupled receptor 174
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Human non-orphan GPCRs

GPR174 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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