GPR174

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
GPR174
HGNC name
G protein-coupled receptor 174
Family
Orphan receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=145
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Description

Figure. Concentration-dependent activation of GPR174 by LPS. Reporter cells were transfected with either the expression plasmid for G protein-coupled receptor 174 (GPR174) or the mock plasmid and treated with various concentrations of lipo­poly­sac­cha­ride (LPS). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 22 nM.