OXGR1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
OXGR1
HGNC name
oxoglutarate receptor 1
Family
Oxoglutarate receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=162
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Description

Figure. Concentration-dependent activation of OXGR1 by 2-oxoglutaric acid. Reporter cells were transfected with either the expression plasmid for oxo­glu­tarate receptor 1 (OXGR1) or the mock plasmid and treated with various concentrations of 2-oxoglutaric acid. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 66 µM.