P2RY12

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
P2RY12
HGNC name
purinergic receptor P2Y12
Family
P2Y receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=328
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Description

Figure. Concentration-dependent activation of P2RY12 by ADP. Reporter cells were transfected with either the expression plasmid for purin­ergic receptor P2Y12 (P2RY12) or the mock plasmid and treated with various concentrations of adeno­sine di­phos­phate (ADP). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 3.0 µM.