Figure. Concentration-dependent activation of P2RY14 by UDP-glucose. Reporter cells were transfected with either the expression plasmid for purin­ergic receptor P2Y14 (P2RY14) or the mock plasmid and treated with various concentrations of UDP-glucose. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 160 nM.