Figure. Concentration-dependent activation of PTGDR by BW245C. Reporter cells were transfected with either the expression plasmid for prosta­gland­in D2 receptor (PTGDR) or the mock plasmid and treated with various concentrations of BW245C. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 380 pM.