Human PTGIR

Figure. Concentration-dependent activation of PTGIR by beraprost

Reporter cells were transfected with either the expression plasmid for human prostaglandin I2 receptor (PTGIR) or the mock plasmid and treated with various concentrations of beraprost. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 130 nM.