Figure. Concentration-dependent activation of F2R by TFLLR-NH2. Reporter cells were transfected with the expression plasmid for co­ag­u­la­tion factor II throm­bin receptor (F2R) and treated with various concentrations of TFLLR-NH2. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 180 nM.