F2R

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
F2R
HGNC name
coagulation factor II thrombin receptor
Family
Proteinase-activated receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=347
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Description

Figure. Concentration-dependent activation of F2R by TFLLR-NH2. Reporter cells were transfected with the expression plasmid for co­ag­u­la­tion factor II throm­bin receptor (F2R) and treated with various concentrations of TFLLR-NH2. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 180 nM.