GPR183

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
GPR183
HGNC name
G protein-coupled receptor 183
Family
Steroid receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=81
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Description

Figure. Concentration-dependent activation of GPR183 by 7α,25-di­hydroxy­cholesterol. Reporter cells were transfected with either the expression plasmid for G protein-coupled receptor 183 (GPR183) or the mock plasmid and treated with various concentrations of 7α,25-di­hydroxy­cholesterol. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 2.0 nM.