Human TRHR

Figure. Concentration-dependent activation of TRHR by TRH

Reporter cells were transfected with either the expression plasmid for human thyrotropin releasing hormone receptor (TRHR) or the mock plasmid and treated with various concentrations of TRH. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 160 pM.