AVPR1B

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
AVPR1B
HGNC name
arginine vasopressin receptor 1B
Family
Vasopressin and oxytocin receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=367
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Description

Figure. Concentration-dependent activation of AVPR1B by [R]-vaso­pressin. Reporter cells were transfected with either the expression plasmid for arginine vaso­pressin receptor 1B (AVPR1B) or the mock plasmid and treated with various concentrations of [R]-vaso­pressin. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 840 pM.

CTA2

Our functional assay platform can test potencies of compounds on more than 300 GPCRs sensitively and reliably in agonist/inverse agonist/antagonist/PAM/NAM modes.


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