ADCYAP1R1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
ADCYAP1R1
HGNC name
ADCYAP receptor type I
Family
VIP and PACAP receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=370

Description

Figure. Concentration-dependent activation of ADCYAP1R1 by PACAP. Reporter cells were transfected with either the expression plasmid for ADCYAP receptor type I (ADCYAP1R1) or the mock plasmid and treated with various concentrations of pi­tu­i­tary adenyl­ate cy­clase-acti­vat­ing poly­pep­tide (PACAP). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 4.4 nM.