Description
Figure. Concentration-dependent activation of ADCYAP1R1 by PACAP. Reporter cells were transfected with either the expression plasmid for ADCYAP receptor type I (ADCYAP1R1) or the mock plasmid and treated with various concentrations of pituitary adenylate cyclase-activating polypeptide (PACAP). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 4.4 nM.