フォーカスドGPCRパネル
FlexPanel48

タンソーバイオサイエンスの独自技術による高感度・網羅的GPCR活性アッセイ技術 (国際特許出願中) を活用した、ヒト48受容体のお求めやすくカスタマイズ自在なパネルサービスです。受容体をいちから自由に選べるカスタムパネルと13の疾患領域パネルがあります。

カスタムパネル

  • リガンド既知受容体202種、オーファン受容体95種から任意の48種を自在に選択可能
  • アッセイモードはアゴニストモード、アンタゴニストモードの2通り *オーファン受容体はアゴニストモードのみ
  • 同一パネル内でアゴニストモード、アンタゴニストモードを混在させることも可能
  • FlexPanel48 対応GPCR全297種一覧・カスタムパネル受容体選択のページはこちら

疾患領域パネル13種

免疫・感染症がん血液内分泌・代謝精神疾患神経眼科 循環器呼吸器消化器皮膚筋骨格系泌尿器・生殖
  • DisGeNETの遺伝子疾患関連情報を基に選択した、各疾患領域との関連性が高いGPCR48種のパネル
  • アッセイモードはアゴニストモード、アンタゴニストモードの2通り
  • 同一パネル内でアッセイモードを混在させることも可能
  • FlexPanel48対応GPCR全297種一覧のページにて疾患領域パネルの受容体を入れ替え、高度なカスタマイズが可能
  • 疾患領域パネル受容体一覧はこちら

FlexPanel48 実施例

内分泌代謝領域・アゴニストモード

TAK875 vs FlexPanel48 Metabol/EndocrinolTAK875 Concentration-response curve
FlexPanel48 内分泌・代謝パネルを用いた糖尿病開発薬TAK-875のアゴニストモードアッセイ。長鎖脂肪酸受容体 FFAR1に選択的なアゴニスト活性が見られ、濃度依存性も確認された。
内分泌・代謝領域パネル受容体
1HTR2A11CALCR21FFAR131KISS1R41PTH1R
2HTR2C12CASR22GHSR32S1PR242PROKR2
3CHRM213CNR123GHRHR33MC1R43PTGER4
4CHRM314CCR524GIPR34MC2R44SSTR1
5ADRA1A15CXCR425GLP1R35MC4R45SSTR2
6ADRB116CCKAR26GCGR36MTNR1B46TACR3
7ADRB217CCKBR27FSHR37NPY1R47TRHR
8ADRB318DRD228LHCGR38NPY2R48AVPR2
9AGTR119EDNRA29TSHR39NPY5R
10BRS320EDNRB30GNRHR40OPRM1

精神疾患領域・アンタゴニストモード

Naloxone vs FlexPanel48-Psychiatry Naloxone Concentration-response curve
FlexPanel48 精神疾患パネルを用いた、オピオイド中毒治療薬naloxoneのアンタゴニストモードアッセイ。オピオイド受容体 OPRD1, OPRK1, OPRM1に選択的なアンタゴニスト活性が見られ、それぞれの受容体で濃度依存性が確認された。
精神疾患領域パネル受容体
1HTR1A11CHRM421CCKBR31HRH141OPRK1
2HTR1B12CHRM522CRHR132HRH242OPRM1
3HTR2A13ADORA2A23CRHR233HRH343OPRL1
4HTR2C14ADRA2A24DRD134GRM244HCRTR1
5HTR5A15ADRA2B25DRD235GRM845TACR1
6HTR616ADRB126DRD336NPSR146AVPR1A
7HTR717ADRB227DRD437NPY1R47OXTR
8CHRM118GRPR28DRD538NPY2R48ADCYAP1R1
9CHRM219CNR129EDNRA39NTSR1
10CHRM320CCKAR30GABBR1/240OPRD1

大規模網羅的パネル

リガンド既知受容体202種、オーファン受容体95種を対象に、より大規模なパネルアッセイも可能です。
パネル対応GPCR全297種一覧
リガンド既知GPCR 200種に対する、降圧薬carvedilolのアンタゴニストモードアッセイ。アドレナリン受容体α1A, α1B, α1D, β1, β2に選択的なアンタゴニスト活性が見られ、それぞれの受容体で濃度依存性が確認された。

FlexPanel48 疾患領域パネル受容体一覧

免疫・感染症がん血液内分泌・代謝精神疾患神経眼科循環器呼吸器消化器皮膚筋骨格系泌尿器・生殖
SymbolHGNC nameFamily
CHRM2cholinergic receptor muscarinic 2Acetylcholine receptors (muscarinic)
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADORA2Aadenosine A2a receptorAdenosine receptors
ADORA2Badenosine A2b receptorAdenosine receptors
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
BRS3bombesin receptor subtype 3Bombesin receptors
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR4C-C motif chemokine receptor 4Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CCR7C-C motif chemokine receptor 7Chemokine receptors
CCR8C-C motif chemokine receptor 8Chemokine receptors
CCR9C-C motif chemokine receptor 9Chemokine receptors
CXCR1C-X-C motif chemokine receptor 1Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR5C-X-C motif chemokine receptor 5Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
C5AR1complement C5a receptor 1Complement peptide receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
GPR183G protein-coupled receptor 183Steroid receptors
TSHRthyroid stimulating hormone receptorGlycoprotein hormone receptors
HRH1histamine receptor H1Histamine receptors
LTB4Rleukotriene B4 receptorLeukotriene receptors
CYSLTR1cysteinyl leukotriene receptor 1Leukotriene receptors
CYSLTR2cysteinyl leukotriene receptor 2Leukotriene receptors
PTAFRplatelet activating factor receptorPlatelet-activating factor receptor
MC2Rmelanocortin 2 receptorMelanocortin receptors
OPRM1opioid receptor mu 1Opioid receptors
P2RY12purinergic receptor P2Y12P2Y receptors
PTGDR2prostaglandin D2 receptor 2Prostanoid receptors
PTGER2prostaglandin E receptor 2Prostanoid receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
F2RL1F2R like trypsin receptor 1Proteinase-activated receptors
SSTR4somatostatin receptor 4Somatostatin receptors
TACR1tachykinin receptor 1Tachykinin receptors
ADCYAP1R1ADCYAP receptor type IVIP and PACAP receptors
SymbolHGNC nameFamily
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
BRS3bombesin receptor subtype 3Bombesin receptors
GRPRgastrin releasing peptide receptorBombesin receptors
NMBRneuromedin B receptorBombesin receptors
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR4C-C motif chemokine receptor 4Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CCR7C-C motif chemokine receptor 7Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CCKARcholecystokinin A receptorCholecystokinin receptors
CCKBRcholecystokinin B receptorCholecystokinin receptors
CRHR1corticotropin releasing hormone receptor 1Corticotropin-releasing factor receptors
DRD2dopamine receptor D2Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
GHSRgrowth hormone secretagogue receptorGhrelin receptor
GLP1Rglucagon like peptide 1 receptorGlucagon receptor family
FSHRfollicle stimulating hormone receptorGlycoprotein hormone receptors
LHCGRluteinizing hormone/choriogonadotropin receptorGlycoprotein hormone receptors
TSHRthyroid stimulating hormone receptorGlycoprotein hormone receptors
GNRHRgonadotropin releasing hormone receptorGonadotrophin-releasing hormone receptors
HRH4histamine receptor H4Histamine receptors
KISS1RKISS1 receptorKisspeptin receptor
CYSLTR2cysteinyl leukotriene receptor 2Leukotriene receptors
LPAR1lysophosphatidic acid receptor 1Lysophospholipid (LPA) receptors
LPAR3lysophosphatidic acid receptor 3Lysophospholipid (LPA) receptors
S1PR1sphingosine-1-phosphate receptor 1Lysophospholipid (S1P) receptors
MC1Rmelanocortin 1 receptorMelanocortin receptors
GRM1glutamate metabotropic receptor 1Metabotropic glutamate receptors
NTSR1neurotensin receptor 1Neurotensin receptors
PTH1Rparathyroid hormone 1 receptorParathyroid hormone receptors
PTGER1prostaglandin E receptor 1Prostanoid receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
F2RL1F2R like trypsin receptor 1Proteinase-activated receptors
SSTR1somatostatin receptor 1Somatostatin receptors
SSTR2somatostatin receptor 2Somatostatin receptors
SSTR4somatostatin receptor 4Somatostatin receptors
SymbolHGNC nameFamily
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
BRS3bombesin receptor subtype 3Bombesin receptors
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR4C-C motif chemokine receptor 4Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CCR7C-C motif chemokine receptor 7Chemokine receptors
CCR8C-C motif chemokine receptor 8Chemokine receptors
CCR9C-C motif chemokine receptor 9Chemokine receptors
CCR10C-C motif chemokine receptor 10Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR5C-X-C motif chemokine receptor 5Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
C5AR1complement C5a receptor 1Complement peptide receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
GPR183G protein-coupled receptor 183Steroid receptors
GLP1Rglucagon like peptide 1 receptorGlucagon receptor family
CYSLTR1cysteinyl leukotriene receptor 1Leukotriene receptors
PTAFRplatelet activating factor receptorPlatelet-activating factor receptor
S1PR1sphingosine-1-phosphate receptor 1Lysophospholipid (S1P) receptors
S1PR2sphingosine-1-phosphate receptor 2Lysophospholipid (S1P) receptors
NPY5Rneuropeptide Y receptor Y5Neuropeptide Y receptors
OPRK1opioid receptor kappa 1Opioid receptors
OPRM1opioid receptor mu 1Opioid receptors
P2RY12purinergic receptor P2Y12P2Y receptors
PTH1Rparathyroid hormone 1 receptorParathyroid hormone receptors
PTGDRprostaglandin D2 receptorProstanoid receptors
PTGDR2prostaglandin D2 receptor 2Prostanoid receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
F2RL3F2R like thrombin or trypsin receptor 3Proteinase-activated receptors
RXFP1relaxin family peptide receptor 1Relaxin family peptide receptors
SSTR4somatostatin receptor 4Somatostatin receptors
TACR1tachykinin receptor 1Tachykinin receptors
ADCYAP1R1ADCYAP receptor type IVIP and PACAP receptors
VIPR1vasoactive intestinal peptide receptor 1VIP and PACAP receptors
SymbolHGNC nameFamily
HTR2A5-hydroxytryptamine receptor 2A5-Hydroxytryptamine receptors
HTR2C5-hydroxytryptamine receptor 2C5-Hydroxytryptamine receptors
CHRM2cholinergic receptor muscarinic 2Acetylcholine receptors (muscarinic)
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRB1adrenoceptor beta 1Adrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
ADRB3adrenoceptor beta 3Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
BRS3bombesin receptor subtype 3Bombesin receptors
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CCKARcholecystokinin A receptorCholecystokinin receptors
CCKBRcholecystokinin B receptorCholecystokinin receptors
DRD2dopamine receptor D2Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
FFAR1free fatty acid receptor 1Free fatty acid receptors
GHSRgrowth hormone secretagogue receptorGhrelin receptor
GHRHRgrowth hormone releasing hormone receptorGlucagon receptor family
GIPRgastric inhibitory polypeptide receptorGlucagon receptor family
GLP1Rglucagon like peptide 1 receptorGlucagon receptor family
GCGRglucagon receptorGlucagon receptor family
FSHRfollicle stimulating hormone receptorGlycoprotein hormone receptors
LHCGRluteinizing hormone/choriogonadotropin receptorGlycoprotein hormone receptors
TSHRthyroid stimulating hormone receptorGlycoprotein hormone receptors
GNRHRgonadotropin releasing hormone receptorGonadotrophin-releasing hormone receptors
KISS1RKISS1 receptorKisspeptin receptor
S1PR2sphingosine-1-phosphate receptor 2Lysophospholipid (S1P) receptors
MC1Rmelanocortin 1 receptorMelanocortin receptors
MC2Rmelanocortin 2 receptorMelanocortin receptors
MC4Rmelanocortin 4 receptorMelanocortin receptors
MTNR1Bmelatonin receptor 1BMelatonin receptors
NPY1Rneuropeptide Y receptor Y1Neuropeptide Y receptors
NPY2Rneuropeptide Y receptor Y2Neuropeptide Y receptors
NPY5Rneuropeptide Y receptor Y5Neuropeptide Y receptors
OPRM1opioid receptor mu 1Opioid receptors
PTH1Rparathyroid hormone 1 receptorParathyroid hormone receptors
PROKR2prokineticin receptor 2Prokineticin receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
SSTR1somatostatin receptor 1Somatostatin receptors
SSTR2somatostatin receptor 2Somatostatin receptors
TACR3tachykinin receptor 3Tachykinin receptors
TRHRthyrotropin releasing hormone receptorThyrotropin-releasing hormone receptors
AVPR2arginine vasopressin receptor 2Vasopressin and oxytocin receptors
SymbolHGNC nameFamily
HTR1A5-hydroxytryptamine receptor 1A5-Hydroxytryptamine receptors
HTR1B5-hydroxytryptamine receptor 1B5-Hydroxytryptamine receptors
HTR2A5-hydroxytryptamine receptor 2A5-Hydroxytryptamine receptors
HTR2C5-hydroxytryptamine receptor 2C5-Hydroxytryptamine receptors
HTR5A5-hydroxytryptamine receptor 5A5-Hydroxytryptamine receptors
HTR65-hydroxytryptamine receptor 65-Hydroxytryptamine receptors
HTR75-hydroxytryptamine receptor 75-Hydroxytryptamine receptors
CHRM1cholinergic receptor muscarinic 1Acetylcholine receptors (muscarinic)
CHRM2cholinergic receptor muscarinic 2Acetylcholine receptors (muscarinic)
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
CHRM4cholinergic receptor muscarinic 4Acetylcholine receptors (muscarinic)
CHRM5cholinergic receptor muscarinic 5Acetylcholine receptors (muscarinic)
ADORA2Aadenosine A2a receptorAdenosine receptors
ADRA2Aadrenoceptor alpha 2AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB1adrenoceptor beta 1Adrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
GRPRgastrin releasing peptide receptorBombesin receptors
CNR1cannabinoid receptor 1Cannabinoid receptors
CCKARcholecystokinin A receptorCholecystokinin receptors
CCKBRcholecystokinin B receptorCholecystokinin receptors
CRHR1corticotropin releasing hormone receptor 1Corticotropin-releasing factor receptors
CRHR2corticotropin releasing hormone receptor 2Corticotropin-releasing factor receptors
DRD1dopamine receptor D1Dopamine receptors
DRD2dopamine receptor D2Dopamine receptors
DRD3dopamine receptor D3Dopamine receptors
DRD4dopamine receptor D4Dopamine receptors
DRD5dopamine receptor D5Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
GABBR1/2gamma-aminobutyric acid type B receptor subunits 1/2GABAB receptors
HRH1histamine receptor H1Histamine receptors
HRH2histamine receptor H2Histamine receptors
HRH3histamine receptor H3Histamine receptors
GRM2glutamate metabotropic receptor 2Metabotropic glutamate receptors
GRM8glutamate metabotropic receptor 8Metabotropic glutamate receptors
NPSR1neuropeptide S receptor 1Neuropeptide S receptor
NPY1Rneuropeptide Y receptor Y1Neuropeptide Y receptors
NPY2Rneuropeptide Y receptor Y2Neuropeptide Y receptors
NTSR1neurotensin receptor 1Neurotensin receptors
OPRD1opioid receptor delta 1Opioid receptors
OPRK1opioid receptor kappa 1Opioid receptors
OPRM1opioid receptor mu 1Opioid receptors
OPRL1opioid related nociceptin receptor 1Opioid receptors
HCRTR1hypocretin receptor 1Orexin receptors
TACR1tachykinin receptor 1Tachykinin receptors
AVPR1Aarginine vasopressin receptor 1AVasopressin and oxytocin receptors
OXTRoxytocin receptorVasopressin and oxytocin receptors
ADCYAP1R1ADCYAP receptor type IVIP and PACAP receptors
SymbolHGNC nameFamily
HTR1A5-hydroxytryptamine receptor 1A5-Hydroxytryptamine receptors
HTR1B5-hydroxytryptamine receptor 1B5-Hydroxytryptamine receptors
HTR2A5-hydroxytryptamine receptor 2A5-Hydroxytryptamine receptors
HTR2C5-hydroxytryptamine receptor 2C5-Hydroxytryptamine receptors
HTR75-hydroxytryptamine receptor 75-Hydroxytryptamine receptors
CHRM1cholinergic receptor muscarinic 1Acetylcholine receptors (muscarinic)
CHRM2cholinergic receptor muscarinic 2Acetylcholine receptors (muscarinic)
CHRM4cholinergic receptor muscarinic 4Acetylcholine receptors (muscarinic)
ADORA1adenosine A1 receptorAdenosine receptors
ADORA2Aadenosine A2a receptorAdenosine receptors
ADRA1Badrenoceptor alpha 1BAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR7C-C motif chemokine receptor 7Chemokine receptors
CCR9C-C motif chemokine receptor 9Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
CCKBRcholecystokinin B receptorCholecystokinin receptors
CRHR1corticotropin releasing hormone receptor 1Corticotropin-releasing factor receptors
DRD1dopamine receptor D1Dopamine receptors
DRD2dopamine receptor D2Dopamine receptors
DRD3dopamine receptor D3Dopamine receptors
DRD4dopamine receptor D4Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
GABBR1/2gamma-aminobutyric acid type B receptor subunits 1/2GABAB receptors
HRH3histamine receptor H3Histamine receptors
KISS1RKISS1 receptorKisspeptin receptor
MC1Rmelanocortin 1 receptorMelanocortin receptors
GRM1glutamate metabotropic receptor 1Metabotropic glutamate receptors
NPY1Rneuropeptide Y receptor Y1Neuropeptide Y receptors
NPY2Rneuropeptide Y receptor Y2Neuropeptide Y receptors
OPRK1opioid receptor kappa 1Opioid receptors
OPRM1opioid receptor mu 1Opioid receptors
PROKR2prokineticin receptor 2Prokineticin receptors
PTGER1prostaglandin E receptor 1Prostanoid receptors
SSTR1somatostatin receptor 1Somatostatin receptors
SSTR2somatostatin receptor 2Somatostatin receptors
SSTR3somatostatin receptor 3Somatostatin receptors
SSTR4somatostatin receptor 4Somatostatin receptors
SSTR5somatostatin receptor 5Somatostatin receptors
TACR1tachykinin receptor 1Tachykinin receptors
TACR3tachykinin receptor 3Tachykinin receptors
SymbolHGNC nameFamily
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADORA2Aadenosine A2a receptorAdenosine receptors
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
BRS3bombesin receptor subtype 3Bombesin receptors
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CCR7C-C motif chemokine receptor 7Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR5C-X-C motif chemokine receptor 5Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
DRD5dopamine receptor D5Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
FFAR4free fatty acid receptor 4Free fatty acid receptors
GHSRgrowth hormone secretagogue receptorGhrelin receptor
GLP1Rglucagon like peptide 1 receptorGlucagon receptor family
TSHRthyroid stimulating hormone receptorGlycoprotein hormone receptors
HCAR2hydroxycarboxylic acid receptor 2Hydroxycarboxylic acid receptors
KISS1RKISS1 receptorKisspeptin receptor
CYSLTR2cysteinyl leukotriene receptor 2Leukotriene receptors
OXER1oxoeicosanoid receptor 1Leukotriene receptors
PTAFRplatelet activating factor receptorPlatelet-activating factor receptor
LPAR3lysophosphatidic acid receptor 3Lysophospholipid (LPA) receptors
LPAR6lysophosphatidic acid receptor 6Lysophospholipid (LPA) receptors
MC1Rmelanocortin 1 receptorMelanocortin receptors
MTNR1Amelatonin receptor 1AMelatonin receptors
GRM1glutamate metabotropic receptor 1Metabotropic glutamate receptors
GRM6glutamate metabotropic receptor 6Metabotropic glutamate receptors
PTH1Rparathyroid hormone 1 receptorParathyroid hormone receptors
PROKR2prokineticin receptor 2Prokineticin receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
PTGFRprostaglandin F receptorProstanoid receptors
F2RL1F2R like trypsin receptor 1Proteinase-activated receptors
SSTR4somatostatin receptor 4Somatostatin receptors
SUCNR1succinate receptor 1Succinate receptor
TACR3tachykinin receptor 3Tachykinin receptors
VIPR2vasoactive intestinal peptide receptor 2VIP and PACAP receptors
SymbolHGNC nameFamily
HTR1B5-hydroxytryptamine receptor 1B5-Hydroxytryptamine receptors
HTR2B5-hydroxytryptamine receptor 2B5-Hydroxytryptamine receptors
HTR45-hydroxytryptamine receptor 45-Hydroxytryptamine receptors
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADORA1adenosine A1 receptorAdenosine receptors
ADORA2Aadenosine A2a receptorAdenosine receptors
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA1Badrenoceptor alpha 1BAdrenoceptors
ADRA2Aadrenoceptor alpha 2AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRA2Cadrenoceptor alpha 2CAdrenoceptors
ADRB1adrenoceptor beta 1Adrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
ADRB3adrenoceptor beta 3Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
APLNRapelin receptorApelin receptor
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
CRHR2corticotropin releasing hormone receptor 2Corticotropin-releasing factor receptors
DRD2dopamine receptor D2Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
GHSRgrowth hormone secretagogue receptorGhrelin receptor
GLP1Rglucagon like peptide 1 receptorGlucagon receptor family
HRH1histamine receptor H1Histamine receptors
HRH3histamine receptor H3Histamine receptors
PTAFRplatelet activating factor receptorPlatelet-activating factor receptor
OPRD1opioid receptor delta 1Opioid receptors
OPRK1opioid receptor kappa 1Opioid receptors
OPRM1opioid receptor mu 1Opioid receptors
P2RY1purinergic receptor P2Y1P2Y receptors
P2RY12purinergic receptor P2Y12P2Y receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
TACR1tachykinin receptor 1Tachykinin receptors
UTS2Rurotensin 2 receptorUrotensin receptor
AVPR1Aarginine vasopressin receptor 1AVasopressin and oxytocin receptors
AVPR2arginine vasopressin receptor 2Vasopressin and oxytocin receptors
SymbolHGNC nameFamily
HTR2A5-hydroxytryptamine receptor 2A5-Hydroxytryptamine receptors
HTR2B5-hydroxytryptamine receptor 2B5-Hydroxytryptamine receptors
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADORA1adenosine A1 receptorAdenosine receptors
ADORA2Aadenosine A2a receptorAdenosine receptors
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
BRS3bombesin receptor subtype 3Bombesin receptors
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR4C-C motif chemokine receptor 4Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CCR8C-C motif chemokine receptor 8Chemokine receptors
CCR9C-C motif chemokine receptor 9Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
C3AR1complement C3a receptor 1Complement peptide receptors
C5AR1complement C5a receptor 1Complement peptide receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
TSHRthyroid stimulating hormone receptorGlycoprotein hormone receptors
HRH1histamine receptor H1Histamine receptors
CYSLTR1cysteinyl leukotriene receptor 1Leukotriene receptors
CYSLTR2cysteinyl leukotriene receptor 2Leukotriene receptors
PTAFRplatelet activating factor receptorPlatelet-activating factor receptor
NPSR1neuropeptide S receptor 1Neuropeptide S receptor
OPRM1opioid receptor mu 1Opioid receptors
P2RY12purinergic receptor P2Y12P2Y receptors
PTH1Rparathyroid hormone 1 receptorParathyroid hormone receptors
PTGDR2prostaglandin D2 receptor 2Prostanoid receptors
PTGER2prostaglandin E receptor 2Prostanoid receptors
PTGFRprostaglandin F receptorProstanoid receptors
PTGIRprostaglandin I2 receptorProstanoid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
F2RL1F2R like trypsin receptor 1Proteinase-activated receptors
SSTR4somatostatin receptor 4Somatostatin receptors
TACR1tachykinin receptor 1Tachykinin receptors
TACR2tachykinin receptor 2Tachykinin receptors
OXTRoxytocin receptorVasopressin and oxytocin receptors
ADCYAP1R1ADCYAP receptor type IVIP and PACAP receptors
SymbolHGNC nameFamily
HTR1A5-hydroxytryptamine receptor 1A5-Hydroxytryptamine receptors
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADORA3adenosine A3 receptorAdenosine receptors
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB1adrenoceptor beta 1Adrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
GPBAR1G protein-coupled bile acid receptor 1Bile acid receptor
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR4C-C motif chemokine receptor 4Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CCR7C-C motif chemokine receptor 7Chemokine receptors
CXCR1C-X-C motif chemokine receptor 1Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR5C-X-C motif chemokine receptor 5Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
CCKARcholecystokinin A receptorCholecystokinin receptors
CCKBRcholecystokinin B receptorCholecystokinin receptors
CRHR2corticotropin releasing hormone receptor 2Corticotropin-releasing factor receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
FPR2formyl peptide receptor 2Formylpeptide receptors
GHSRgrowth hormone secretagogue receptorGhrelin receptor
GLP1Rglucagon like peptide 1 receptorGlucagon receptor family
HRH2histamine receptor H2Histamine receptors
HRH4histamine receptor H4Histamine receptors
KISS1RKISS1 receptorKisspeptin receptor
LTB4Rleukotriene B4 receptorLeukotriene receptors
PTAFRplatelet activating factor receptorPlatelet-activating factor receptor
LPAR1lysophosphatidic acid receptor 1Lysophospholipid (LPA) receptors
OPRM1opioid receptor mu 1Opioid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
F2RL1F2R like trypsin receptor 1Proteinase-activated receptors
F2RL3F2R like thrombin or trypsin receptor 3Proteinase-activated receptors
SSTR1somatostatin receptor 1Somatostatin receptors
SSTR2somatostatin receptor 2Somatostatin receptors
SSTR3somatostatin receptor 3Somatostatin receptors
TACR1tachykinin receptor 1Tachykinin receptors
VIPR1vasoactive intestinal peptide receptor 1VIP and PACAP receptors
SymbolHGNC nameFamily
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADORA2Aadenosine A2a receptorAdenosine receptors
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA2Aadrenoceptor alpha 2AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
BRS3bombesin receptor subtype 3Bombesin receptors
NMBRneuromedin B receptorBombesin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR4C-C motif chemokine receptor 4Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CCR7C-C motif chemokine receptor 7Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR5C-X-C motif chemokine receptor 5Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
CRHR1corticotropin releasing hormone receptor 1Corticotropin-releasing factor receptors
DRD2dopamine receptor D2Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
LHCGRluteinizing hormone/choriogonadotropin receptorGlycoprotein hormone receptors
TSHRthyroid stimulating hormone receptorGlycoprotein hormone receptors
HRH1histamine receptor H1Histamine receptors
HRH4histamine receptor H4Histamine receptors
HCAR2hydroxycarboxylic acid receptor 2Hydroxycarboxylic acid receptors
HCAR3hydroxycarboxylic acid receptor 3Hydroxycarboxylic acid receptors
KISS1RKISS1 receptorKisspeptin receptor
LPAR1lysophosphatidic acid receptor 1Lysophospholipid (LPA) receptors
LPAR6lysophosphatidic acid receptor 6Lysophospholipid (LPA) receptors
MC1Rmelanocortin 1 receptorMelanocortin receptors
GRM1glutamate metabotropic receptor 1Metabotropic glutamate receptors
OPRM1opioid receptor mu 1Opioid receptors
P2RY12purinergic receptor P2Y12P2Y receptors
PROKR2prokineticin receptor 2Prokineticin receptors
PTGER1prostaglandin E receptor 1Prostanoid receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
F2RL1F2R like trypsin receptor 1Proteinase-activated receptors
SSTR4somatostatin receptor 4Somatostatin receptors
TACR1tachykinin receptor 1Tachykinin receptors
UTS2Rurotensin 2 receptorUrotensin receptor
SymbolHGNC nameFamily
HTR75-hydroxytryptamine receptor 75-Hydroxytryptamine receptors
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADORA2Aadenosine A2a receptorAdenosine receptors
ADRA2Aadrenoceptor alpha 2AAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CCR1C-C motif chemokine receptor 1Chemokine receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CCR7C-C motif chemokine receptor 7Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR5C-X-C motif chemokine receptor 5Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
C5AR1complement C5a receptor 1Complement peptide receptors
CRHR1corticotropin releasing hormone receptor 1Corticotropin-releasing factor receptors
DRD2dopamine receptor D2Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
GABBR1/2gamma-aminobutyric acid type B receptor subunits 1/2GABAB receptors
GHSRgrowth hormone secretagogue receptorGhrelin receptor
GHRHRgrowth hormone releasing hormone receptorGlucagon receptor family
GLP1Rglucagon like peptide 1 receptorGlucagon receptor family
FSHRfollicle stimulating hormone receptorGlycoprotein hormone receptors
TSHRthyroid stimulating hormone receptorGlycoprotein hormone receptors
GNRHRgonadotropin releasing hormone receptorGonadotrophin-releasing hormone receptors
KISS1RKISS1 receptorKisspeptin receptor
LPAR1lysophosphatidic acid receptor 1Lysophospholipid (LPA) receptors
MC1Rmelanocortin 1 receptorMelanocortin receptors
MC2Rmelanocortin 2 receptorMelanocortin receptors
GRM1glutamate metabotropic receptor 1Metabotropic glutamate receptors
PTH1Rparathyroid hormone 1 receptorParathyroid hormone receptors
PTH2Rparathyroid hormone 2 receptorParathyroid hormone receptors
PROKR2prokineticin receptor 2Prokineticin receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
F2RL1F2R like trypsin receptor 1Proteinase-activated receptors
SSTR4somatostatin receptor 4Somatostatin receptors
TACR1tachykinin receptor 1Tachykinin receptors
TACR3tachykinin receptor 3Tachykinin receptors
TRHRthyrotropin releasing hormone receptorThyrotropin-releasing hormone receptors
AVPR2arginine vasopressin receptor 2Vasopressin and oxytocin receptors
SymbolHGNC nameFamily
CHRM2cholinergic receptor muscarinic 2Acetylcholine receptors (muscarinic)
CHRM3cholinergic receptor muscarinic 3Acetylcholine receptors (muscarinic)
ADRA1Aadrenoceptor alpha 1AAdrenoceptors
ADRA2Badrenoceptor alpha 2BAdrenoceptors
ADRB2adrenoceptor beta 2Adrenoceptors
AGTR1angiotensin II receptor type 1Angiotensin receptors
BRS3bombesin receptor subtype 3Bombesin receptors
GRPRgastrin releasing peptide receptorBombesin receptors
CALCRcalcitonin receptorCalcitonin receptors
CASRcalcium sensing receptorCalcium-sensing receptor
CNR1cannabinoid receptor 1Cannabinoid receptors
CMKLR1chemerin chemokine-like receptor 1Chemerin receptors
CCR2C-C motif chemokine receptor 2Chemokine receptors
CCR5C-C motif chemokine receptor 5 (gene/pseudogene)Chemokine receptors
CCR6C-C motif chemokine receptor 6Chemokine receptors
CXCR2C-X-C motif chemokine receptor 2Chemokine receptors
CXCR3C-X-C motif chemokine receptor 3Chemokine receptors
CXCR4C-X-C motif chemokine receptor 4Chemokine receptors
CXCR6C-X-C motif chemokine receptor 6Chemokine receptors
CX3CR1C-X3-C motif chemokine receptor 1Chemokine receptors
DRD1dopamine receptor D1Dopamine receptors
DRD2dopamine receptor D2Dopamine receptors
EDNRAendothelin receptor type AEndothelin receptors
EDNRBendothelin receptor type BEndothelin receptors
GLP1Rglucagon like peptide 1 receptorGlucagon receptor family
FSHRfollicle stimulating hormone receptorGlycoprotein hormone receptors
LHCGRluteinizing hormone/choriogonadotropin receptorGlycoprotein hormone receptors
TSHRthyroid stimulating hormone receptorGlycoprotein hormone receptors
GNRHRgonadotropin releasing hormone receptorGonadotrophin-releasing hormone receptors
KISS1RKISS1 receptorKisspeptin receptor
PTAFRplatelet activating factor receptorPlatelet-activating factor receptor
LPAR1lysophosphatidic acid receptor 1Lysophospholipid (LPA) receptors
MC2Rmelanocortin 2 receptorMelanocortin receptors
MTNR1Bmelatonin receptor 1BMelatonin receptors
PTH1Rparathyroid hormone 1 receptorParathyroid hormone receptors
PROKR2prokineticin receptor 2Prokineticin receptors
PTGER1prostaglandin E receptor 1Prostanoid receptors
PTGER2prostaglandin E receptor 2Prostanoid receptors
PTGER4prostaglandin E receptor 4Prostanoid receptors
PTGFRprostaglandin F receptorProstanoid receptors
F2Rcoagulation factor II thrombin receptorProteinase-activated receptors
RXFP1relaxin family peptide receptor 1Relaxin family peptide receptors
RXFP2relaxin family peptide receptor 2Relaxin family peptide receptors
SSTR4somatostatin receptor 4Somatostatin receptors
TACR3tachykinin receptor 3Tachykinin receptors
UTS2Rurotensin 2 receptorUrotensin receptor
AVPR1Aarginine vasopressin receptor 1AVasopressin and oxytocin receptors
AVPR2arginine vasopressin receptor 2Vasopressin and oxytocin receptors