Complement peptide receptors
Overview
Complement peptide receptors are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a and C5a, generated upon stimulation of the complement cascade. C3a and C5a exert their functions through binding to their receptors (C3aR, C5aR1 and C5aR2), causing cell recruitment and triggering cellular degranulation that contributes to local inflammation.Excerpt from IUPHAR/BPS Guide to Pharmacology Filters Sort resultsReset ApplySpeciesFamilyPanelDownload CatalogFilters Sort resultsReset Apply
Species Receptor Family Assays Human AvailableAssay modes:-Panels: Human AvailableAssay modes:-Panels: Human UnavailableAssay modes:-Panels:- Reference agonist:EC50: Mouse AvailableAssay modes:-Panels: Mouse AvailableAssay modes:-Panels: Manage ConsentTo provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.Functional Always activeThe technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.PreferencesThe technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.StatisticsThe technical storage or access that is used exclusively for statistical purposes. The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.MarketingThe technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.Manage ConsentTo provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.Functional Always activeThe technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.PreferencesThe technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.StatisticsThe technical storage or access that is used exclusively for statistical purposes. The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.MarketingThe technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.トップへ戻る