Human C3AR1

Figure. Concentration-dependent activation of C3AR1 by C3a

Reporter cells were transfected with either the expression plasmid for human complement C3a receptor 1 (C3AR1) or the mock plasmid and treated with various concentrations of C3a. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 3.7 nM.