Angiotensin receptors


The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors, which have around 30% sequence similarity. The decapeptide angiotensin I, the octapeptide angiotensin II and the heptapeptide angiotensin III are endogenous ligands. losartan, candesartan, telmisartan, etc. are clinically used AT1 receptor blockers.
Excerpt from IUPHAR/BPS Guide to Pharmacology
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