Overview
The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors, which have around 30% sequence similarity. The decapeptide angiotensin I, the octapeptide angiotensin II and the heptapeptide angiotensin III are endogenous ligands. losartan, candesartan, telmisartan, etc. are clinically used AT1 receptor blockers.
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