Mouse Agtr1a|Agtr1b

Figure. Concentration-dependent activation of Agtr1a|Agtr1b by angiotensin ⅠⅠ

Reporter cells were transfected with either the expression plasmid for mouse angiotensin ⅠⅠ receptor, type 1a|angiotensin ⅠⅠ receptor, type 1b (Agtr1a|Agtr1b) or the mock plasmid and treated with various concentrations of the reference agonist. Data points shown are the mean ± SEM of an experiment (n = 4).

Nomenclature
angiotensin ⅠⅠ receptor, type 1a|angiotensin ⅠⅠ receptor, type 1b
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Mouse non-orphan GPCRs

Angiotensin receptors

The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors, which have around 30% sequence similarity. The decapeptide angiotensin I, the octapeptide angiotensin II and the heptapeptide angiotensin III are endogenous ligands. losartan, candesartan, telmisartan, etc. are clinically used AT1 receptor blockers.
Excerpt from IUPHAR/BPS Guide to Pharmacology

Related Receptors

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Human
AGTR1
angiotensin ⅠⅠ receptor type 1
Concentration-response curve for AGTR1
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Mouse
Agtr1a|Agtr1b
angiotensin ⅠⅠ receptor, type 1a|angiotensin ⅠⅠ receptor, type 1b