With its innovative functional assay platform for G-protein-coupled receptor (GPCR), Tanso Biosciences promotes human health by expanding frontiers in drug discovery and accelerating research & development.

Core Business

Drug Discovery Enterprise

We take advantage of our all-around assay technology and engage in drug discovery for orphan GPCRs.

Learn more
Contract Services

Panel assays, concentration dependence analysis, and other functional assays for > 300 orphan and non-orphan GPCRs.

Learn more

Assay Platform

Uses

compass
  • On-target and off-target screening for drug discovery
  • Compound profiling
  • Strategy development
  • In-licensing assessment
  • Drug repurposing

Key Features

Potency-Oriented

Characterizes compounds' potency, not affinity, on target GPCR in various modes

Super-Sensitive

Dramatically and specifically amplifies G-protein-dependent signals

All-Around

All GPCRs are amenable in single assay format, regardless of Gα proteins coupled

Voice of Client

Pharma A

Tanso Bio helps us accelerate structure-activity relationship studies.

Pharma B

Tanso Bio's assays have revealed key features of our compounds that would otherwise remain unnoticed.

Assay Examples

Shown below are a few use cases of our assay platform.

Large-Scale Panel

Antagonistic activities of carvedilol against 200 human non-orphan GPCRs

Endocrinol/Metab Panel

TAK-875, an antidiabetic agent, against 48 GPCRs associated with endocrinology and metabolism

Orphan GPCR Screening

Concentration-dependent activation of GPR68 by a newly identified agonist

Proton Sensitivity

Activity of GPR65 at various pH

G12/13

Agonist-induced concentration-dependent activation of LPAR6, a G12/13-coupled receptor

News & Events

Web Updates
Figures for GPR88 & MRGPRX4 AddedNew!!
News
CEO Gives Talk at Nagoya City University
News
タンソーバイオサイエンス全オーファンGPCR創薬 頭書の研究開発プロジェクトは技術の新規性及び事業の発展性に極めて優れ我が国産業経済の発展に資するところ大であると認められますので助成金を交付致します
Tanso to Receive Mitsubishi UFJ's Commendation & Grant
News
日経バイオスタートアップ総覧2021-2022表紙
Nikkei's New Publication Features Tanso Biosciences
Web Updates
Plots of Prostaglandin E2 Receptors Updated
News
Gies College of Business, University of Illinois
CEO Quoted in University of Illinois News

Contact Us

Send us a message via the form below or write to us at [email protected].

Service Flow Chart

Request for Quotation

Tell us about the types of tests you need, the number of compounds, the receptors of interest, and other preferences. A non-disclosure agreement is optional.

STEP
1

Order

A non-disclosure agreement is optional.

STEP
2

Compound Shipment

The client ships test compounds to our laboratory. We usually perform assays and write a report in three weeks from the receipt of the compounds.

STEP
3

Receipt of the Report

We provide the report and raw data for the client via email or a cloud service.

STEP
4

Inquiry & RFQ Form