With its innovative functional assay platform for G-protein-coupled receptors (GPCRs), Tanso Biosciences promotes human health by expanding frontiers in drug discovery and accelerating research & development.
Core Business
Drug Discovery Enterprise
We take advantage of our all-around assay technology and engage in drug discovery for orphan GPCRs.
Contract Services
Panel assays, concentration dependence analysis, and other functional assays for > 300 orphan and non-orphan GPCRs.
Assay Platform
Uses
- On-target and off-target screening for drug discovery
- Compound profiling
- Strategy development
- In-licensing assessment
- Drug repurposing
Key Features
Potency-Oriented
Characterizes compounds' potency, not affinity, on target GPCR in various modes
Super-Sensitive
Dramatically and specifically amplifies G-protein-dependent signals
All-Around
All GPCRs are amenable in single assay format, regardless of Gα proteins coupled
Voice of Client
Tanso Bio helps us accelerate structure-activity relationship studies.
Tanso Bio's assays have revealed key features of our compounds that would otherwise remain unnoticed.
Noteworthy Information
Assay Examples
Shown below are a few use cases of our assay platform.
Endocrinol/Metab Panel
TAK-875, an antidiabetic agent, against 48 GPCRs associated with endocrinology and metabolism
G12/13
Agonist-induced concentration-dependent activation of LPAR6, a G12/13-coupled receptor
News & Updates
Registered by HHMI as VendorNew!!
MeSH Headings for GPCRs Untangled for Effective PubMed Searches
Figures for GPR88 & MRGPRX4 Added
CEO Gives Talk at Nagoya City University
Tanso to Receive Mitsubishi UFJ's Commendation & Grant
Nikkei's New Publication Features Tanso Biosciences
Plots of Prostaglandin E2 Receptors Updated
CEO Quoted in University of Illinois News
Proton Sensitivity Analyses Added
Contact Us
Send us a message via the form below or write to us at [email protected].
Service Flow Chart
Request for Quotation
Tell us about the types of tests you need, the number of compounds, the receptors of interest, and other preferences. A non-disclosure agreement is optional.
Order
A non-disclosure agreement is optional.
Compound Shipment
The client ships test compounds to our laboratory. We usually perform assays and write a report in three weeks from the receipt of the compounds.
Receipt of the Report
We provide the report and raw data for the client via email or a cloud service.
