Human OPRM1

Figure. Concentration-dependent activation of OPRM1 by DAMGO

Reporter cells were transfected with either the expression plasmid for human opioid receptor mu 1 (OPRM1) or the mock plasmid and treated with various concentrations of DAMGO. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 21 nM.

説明

Nomenclature: opioid receptor mu 1
Available assay modes: Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels: à la carte, Immunology/Infection, Hematology, Endocrinology/Metabolism, Psychiatry, Neurology, Cardiology, Respiratory, Gastrointestinal, Dermatology, Human non-orphan GPCRs

OPRM1 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors


Human	OPRD1 opioid receptor delta 1
Human	OPRK1 opioid receptor kappa 1
Human	OPRM1 opioid receptor mu 1
Human	OPRL1 opioid related nociceptin receptor 1
Mouse	Oprd1 opioid receptor, delta 1
Mouse	Oprk1 opioid receptor, kappa 1
Mouse	Oprm1 opioid receptor, mu 1
Mouse	Oprl1 opioid receptor-like 1

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