HTR6

Figure. Concentration-dependent activation of HTR6 by serotonin
Reporter cells were transfected with either the expression plasmid for 5-hydroxytryptamine receptor 6 (HTR6) or the mock plasmid and treated with various concentrations of serotonin. Data points shown are the mean ± SEM of an experiment, and the curve is a fit to Hill equation with an EC50 of 8.6 nM.
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
Psychiatry, Non-orphan GPCRs
Symbol
HTR6
Nomenclature
5-hydroxytryptamine receptor 6
Family
Species
Human