ヒトGPCRパネルアッセイ

タンソーバイオサイエンスの独自技術による高感度・網羅的活性GPCRアッセイ技術（国際特許出願中）を活用したヒトGPCRパネルサービスです。

GPCR 294種から48受容体を自由に選べる FlexPanel48 カスタムパネル
13疾患領域に関連性が高いGPCR 各48種を取り揃えた FlexPanel48 疾患領域パネル
最大294受容体の大規模網羅的パネル

パネルアッセイ対象の全294受容体一覧表はこちら。
フォームまたはメールにてお気軽にお問い合わせください。

フォーカスドGPCRパネル
FlexPanel48

ヒト48受容体のお求めやすくカスタマイズ自在なパネルサービスです。受容体をいちから自由に選べるカスタムパネルと13の疾患領域パネルがあります。

カスタムパネル

リガンド既知受容体200種、オーファン受容体94種から任意の48種を自在に選択可能
アッセイモードはアゴニストモード、アンタゴニストモードの2通り *オーファン受容体はアゴニストモードのみ
同一パネル内でアゴニストモード、アンタゴニストモードを混在させることも可能

パネル対応全受容体一覧表はこちら

疾患領域パネル

13疾患領域

免疫・感染症
がん
血液
内分泌・代謝
精神疾患
神経
眼科
循環器
呼吸器
消化器
皮膚
筋骨格系
泌尿器・生殖

DisGeNETの遺伝子疾患関連情報を基に選択した、各疾患領域との関連性が高いGPCR 48種のパネル
アッセイモードはアゴニストモード、アンタゴニストモードの2通り
同一パネル内でアッセイモードを混在させることが可能
疾患領域パネルの受容体を入れ替えてカスタマイズすることも可能

疾患領域パネル受容体一覧表はこちら

FlexPanel48 実施例

内分泌代謝領域・アゴニストモード

TAK875 vs FlexPanel48 Metabol/Endocrinol

図1. TAK-875の内分泌代謝領域パネルアッセイ

図2. TAK-875の濃度反応曲線

FlexPanel48 内分泌・代謝パネルを用いた糖尿病開発薬TAK-875のアゴニストモードアッセイ（図1）。長鎖脂肪酸受容体 FFAR1に選択的なアゴニスト活性が見られた。また、濃度依存性も確認された（図2）。

内分泌・代謝領域パネル受容体

1	HTR2A	11	CALCR	21	FFAR1	31	KISS1R	41	PTH1R
2	HTR2C	12	CASR	22	GHSR	32	S1PR2	42	PROKR2
3	CHRM2	13	CNR1	23	GHRHR	33	MC1R	43	PTGER4
4	CHRM3	14	CCR5	24	GIPR	34	MC2R	44	SSTR1
5	ADRA1A	15	CXCR4	25	GLP1R	35	MC4R	45	SSTR2
6	ADRB1	16	CCKAR	26	GCGR	36	MTNR1B	46	TACR3
7	ADRB2	17	CCKBR	27	FSHR	37	NPY1R	47	TRHR
8	ADRB3	18	DRD2	28	LHCGR	38	NPY2R	48	AVPR2
9	AGTR1	19	EDNRA	29	TSHR	39	NPY5R
10	BRS3	20	EDNRB	30	GNRHR	40	OPRM1

精神疾患領域・アンタゴニストモード

図3. Naloxoneの精神科領域パネルアッセイ

図4. Naloxoneの濃度反応曲線

FlexPanel48 精神疾患パネルを用いた、オピオイド中毒治療薬naloxoneのアンタゴニストモードアッセイ（図3）。オピオイド受容体 OPRD1, OPRK1, OPRM1に選択的なアンタゴニスト活性が見られた。また、それぞれの受容体で濃度依存性が確認された（図4）。

精神疾患領域パネル受容体

1	HTR1A	11	CHRM4	21	CCKBR	31	HRH1	41	OPRK1
2	HTR1B	12	CHRM5	22	CRHR1	32	HRH2	42	OPRM1
3	HTR2A	13	ADORA2A	23	CRHR2	33	HRH3	43	OPRL1
4	HTR2C	14	ADRA2A	24	DRD1	34	GRM2	44	HCRTR1
5	HTR5A	15	ADRA2B	25	DRD2	35	GRM8	45	TACR1
6	HTR6	16	ADRB1	26	DRD3	36	NPSR1	46	AVPR1A
7	HTR7	17	ADRB2	27	DRD4	37	NPY1R	47	OXTR
8	CHRM1	18	GRPR	28	DRD5	38	NPY2R	48	ADCYAP1R1
9	CHRM2	19	CNR1	29	EDNRA	39	NTSR1
10	CHRM3	20	CCKAR	30	GABBR1/2	40	OPRD1

大規模網羅的パネル

リガンド既知受容体200種、オーファン受容体94種を対象に、より大規模なパネルアッセイも可能です。パネル対応GPCR全294種一覧表はこちら

図5. Carvedilolの大規模網羅的パネルアッセイ

図6. Carvedilolの濃度反応曲線

リガンド既知GPCR 200種に対する、降圧薬carvedilolのアンタゴニストモードアッセイ（図5）。アドレナリン受容体α_1A, α_1B, α_1D, β₁, β₂に選択的なアンタゴニスト活性が見られた。また、それぞれの受容体で濃度依存性が確認された（図6）。

パネル受容体一覧表

パネル対応全294受容体、疾患領域パネル各48受容体の一覧表です。
疾患領域パネルをカスタマイズし独自のパネルを作ることもできます。

パネル対応全受容体免疫・感染症がん血液内分泌・代謝精神疾患神経眼科循環器呼吸器消化器皮膚筋骨格系泌尿器・生殖

Symbol	HGNC name	Family
HTR1A	5-hydroxytryptamine receptor 1A	5-Hydroxytryptamine receptors
HTR1B	5-hydroxytryptamine receptor 1B	5-Hydroxytryptamine receptors
HTR1D	5-hydroxytryptamine receptor 1D	5-Hydroxytryptamine receptors
HTR1E	5-hydroxytryptamine receptor 1E	5-Hydroxytryptamine receptors
HTR1F	5-hydroxytryptamine receptor 1F	5-Hydroxytryptamine receptors
HTR2A	5-hydroxytryptamine receptor 2A	5-Hydroxytryptamine receptors
HTR2B	5-hydroxytryptamine receptor 2B	5-Hydroxytryptamine receptors
HTR2C	5-hydroxytryptamine receptor 2C	5-Hydroxytryptamine receptors
HTR4	5-hydroxytryptamine receptor 4	5-Hydroxytryptamine receptors
HTR5A	5-hydroxytryptamine receptor 5A	5-Hydroxytryptamine receptors
HTR6	5-hydroxytryptamine receptor 6	5-Hydroxytryptamine receptors
HTR7	5-hydroxytryptamine receptor 7	5-Hydroxytryptamine receptors
CHRM1	cholinergic receptor muscarinic 1	Acetylcholine receptors (muscarinic)
CHRM2	cholinergic receptor muscarinic 2	Acetylcholine receptors (muscarinic)
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
CHRM4	cholinergic receptor muscarinic 4	Acetylcholine receptors (muscarinic)
CHRM5	cholinergic receptor muscarinic 5	Acetylcholine receptors (muscarinic)
ADORA1	adenosine A1 receptor	Adenosine receptors
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADORA2B	adenosine A2b receptor	Adenosine receptors
ADORA3	adenosine A3 receptor	Adenosine receptors
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA1B	adrenoceptor alpha 1B	Adrenoceptors
ADRA1D	adrenoceptor alpha 1D	Adrenoceptors
ADRA2A	adrenoceptor alpha 2A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRA2C	adrenoceptor alpha 2C	Adrenoceptors
ADRB1	adrenoceptor beta 1	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
ADRB3	adrenoceptor beta 3	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
APLNR	apelin receptor	Apelin receptor
GPBAR1	G protein-coupled bile acid receptor 1	Bile acid receptor
BRS3	bombesin receptor subtype 3	Bombesin receptors
GRPR	gastrin releasing peptide receptor	Bombesin receptors
NMBR	neuromedin B receptor	Bombesin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CALCRL	calcitonin receptor like receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
GPR55	G protein-coupled receptor 55	Cannabinoid receptors
GPR119	G protein-coupled receptor 119	Cannabinoid receptors
CMKLR1	chemerin chemokine-like receptor 1	Chemerin receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR4	C-C motif chemokine receptor 4	Chemokine receptors
CCR5	C-C motif chemokine receptor 5	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CCR8	C-C motif chemokine receptor 8	Chemokine receptors
CCR9	C-C motif chemokine receptor 9	Chemokine receptors
CCR10	C-C motif chemokine receptor 10	Chemokine receptors
CXCR1	C-X-C motif chemokine receptor 1	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR5	C-X-C motif chemokine receptor 5	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
CCKAR	cholecystokinin A receptor	Cholecystokinin receptors
CCKBR	cholecystokinin B receptor	Cholecystokinin receptors
C3AR1	complement C3a receptor 1	Complement peptide receptors
C5AR1	complement C5a receptor 1	Complement peptide receptors
CRHR1	corticotropin releasing hormone receptor 1	Corticotropin-releasing factor receptors
CRHR2	corticotropin releasing hormone receptor 2	Corticotropin-releasing factor receptors
DRD1	dopamine receptor D1	Dopamine receptors
DRD2	dopamine receptor D2	Dopamine receptors
DRD3	dopamine receptor D3	Dopamine receptors
DRD4	dopamine receptor D4	Dopamine receptors
DRD5	dopamine receptor D5	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
GPR183	G protein-coupled receptor 183	Steroid receptors
FPR1	formyl peptide receptor 1	Formylpeptide receptors
FPR2	formyl peptide receptor 2	Formylpeptide receptors
FPR3	formyl peptide receptor 3	Formylpeptide receptors
FFAR1	free fatty acid receptor 1	Free fatty acid receptors
FFAR3	free fatty acid receptor 3	Free fatty acid receptors
GPR84	G protein-coupled receptor 84	Free fatty acid receptors
FFAR4	free fatty acid receptor 4	Free fatty acid receptors
GABBR1	gamma-aminobutyric acid type B receptor subunit 1	GABA_B receptors
GABBR2	gamma-aminobutyric acid type B receptor subunit 2	GABA_B receptors
GALR1	galanin receptor 1	Galanin receptors
GALR2	galanin receptor 2	Galanin receptors
GHSR	growth hormone secretagogue receptor	Ghrelin receptor
GHRHR	growth hormone releasing hormone receptor	Glucagon receptor family
GIPR	gastric inhibitory polypeptide receptor	Glucagon receptor family
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
GLP2R	glucagon like peptide 2 receptor	Glucagon receptor family
GCGR	glucagon receptor	Glucagon receptor family
SCTR	secretin receptor	Glucagon receptor family
FSHR	follicle stimulating hormone receptor	Glycoprotein hormone receptors
LHCGR	luteinizing hormone/choriogonadotropin receptor	Glycoprotein hormone receptors
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
GNRHR	gonadotropin releasing hormone receptor	Gonadotrophin-releasing hormone receptors
HRH1	histamine receptor H1	Histamine receptors
HRH2	histamine receptor H2	Histamine receptors
HRH3	histamine receptor H3	Histamine receptors
HRH4	histamine receptor H4	Histamine receptors
HCAR2	hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptors
HCAR3	hydroxycarboxylic acid receptor 3	Hydroxycarboxylic acid receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
LTB4R	leukotriene B4 receptor	Leukotriene receptors
LTB4R2	leukotriene B4 receptor 2	Leukotriene receptors
CYSLTR1	cysteinyl leukotriene receptor 1	Leukotriene receptors
CYSLTR2	cysteinyl leukotriene receptor 2	Leukotriene receptors
PTAFR	platelet activating factor receptor	Platelet-activating factor receptor
LPAR1	lysophosphatidic acid receptor 1	Lysophospholipid (LPA) receptors
LPAR3	lysophosphatidic acid receptor 3	Lysophospholipid (LPA) receptors
LPAR4	lysophosphatidic acid receptor 4	Lysophospholipid (LPA) receptors
LPAR5	lysophosphatidic acid receptor 5	Lysophospholipid (LPA) receptors
LPAR6	lysophosphatidic acid receptor 6	Lysophospholipid (LPA) receptors
S1PR1	sphingosine-1-phosphate receptor 1	Lysophospholipid (S1P) receptors
S1PR2	sphingosine-1-phosphate receptor 2	Lysophospholipid (S1P) receptors
S1PR3	sphingosine-1-phosphate receptor 3	Lysophospholipid (S1P) receptors
S1PR5	sphingosine-1-phosphate receptor 5	Lysophospholipid (S1P) receptors
MCHR1	melanin concentrating hormone receptor 1	Melanin-concentrating hormone receptors
MCHR2	melanin concentrating hormone receptor 2	Melanin-concentrating hormone receptors
MC1R	melanocortin 1 receptor	Melanocortin receptors
MC2R	melanocortin 2 receptor	Melanocortin receptors
MC3R	melanocortin 3 receptor	Melanocortin receptors
MC4R	melanocortin 4 receptor	Melanocortin receptors
MC5R	melanocortin 5 receptor	Melanocortin receptors
MTNR1A	melatonin receptor 1A	Melatonin receptors
MTNR1B	melatonin receptor 1B	Melatonin receptors
GRM1	glutamate metabotropic receptor 1	Metabotropic glutamate receptors
GRM2	glutamate metabotropic receptor 2	Metabotropic glutamate receptors
GRM4	glutamate metabotropic receptor 4	Metabotropic glutamate receptors
GRM6	glutamate metabotropic receptor 6	Metabotropic glutamate receptors
GRM8	glutamate metabotropic receptor 8	Metabotropic glutamate receptors
MLNR	motilin receptor	Motilin receptor
NMUR1	neuromedin U receptor 1	Neuromedin U receptors
NMUR2	neuromedin U receptor 2	Neuromedin U receptors
NPFFR1	neuropeptide FF receptor 1	Neuropeptide FF/neuropeptide AF receptors
NPFFR2	neuropeptide FF receptor 2	Neuropeptide FF/neuropeptide AF receptors
NPBWR1	neuropeptides B and W receptor 1	Neuropeptide W/neuropeptide B receptors
NPBWR2	neuropeptides B and W receptor 2	Neuropeptide W/neuropeptide B receptors
NPY1R	neuropeptide Y receptor Y1	Neuropeptide Y receptors
NPY2R	neuropeptide Y receptor Y2	Neuropeptide Y receptors
NPY4R	neuropeptide Y receptor Y4	Neuropeptide Y receptors
NPY5R	neuropeptide Y receptor Y5	Neuropeptide Y receptors
NTSR1	neurotensin receptor 1	Neurotensin receptors
NTSR2	neurotensin receptor 2	Neurotensin receptors
OPRD1	opioid receptor delta 1	Opioid receptors
OPRK1	opioid receptor kappa 1	Opioid receptors
OPRM1	opioid receptor mu 1	Opioid receptors
OPRL1	opioid related nociceptin receptor 1	Opioid receptors
HCRTR1	hypocretin receptor 1	Orexin receptors
HCRTR2	hypocretin receptor 2	Orexin receptors
OXGR1	oxoglutarate receptor 1	Oxoglutarate receptors
P2RY1	purinergic receptor P2Y1	P2Y receptors
P2RY2	purinergic receptor P2Y2	P2Y receptors
P2RY4	pyrimidinergic receptor P2Y4	P2Y receptors
P2RY6	pyrimidinergic receptor P2Y6	P2Y receptors
P2RY11	purinergic receptor P2Y11	P2Y receptors
P2RY12	purinergic receptor P2Y12	P2Y receptors
P2RY14	purinergic receptor P2Y14	P2Y receptors
P2RY10	P2Y receptor family member 10	P2Y receptors
PTH1R	parathyroid hormone 1 receptor	Parathyroid hormone receptors
PTH2R	parathyroid hormone 2 receptor	Parathyroid hormone receptors
PROKR1	prokineticin receptor 1	Prokineticin receptors
PROKR2	prokineticin receptor 2	Prokineticin receptors
PRLHR	prolactin releasing hormone receptor	Prolactin-releasing peptide receptor
PTGDR	prostaglandin D2 receptor	Prostanoid receptors
PTGDR2	prostaglandin D2 receptor 2	Prostanoid receptors
PTGER1	prostaglandin E receptor 1	Prostanoid receptors
PTGER2	prostaglandin E receptor 2	Prostanoid receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
PTGFR	prostaglandin F receptor	Prostanoid receptors
PTGIR	prostaglandin I2 receptor	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
F2RL1	F2R like trypsin receptor 1	Proteinase-activated receptors
F2RL2	coagulation factor II thrombin receptor like 2	Proteinase-activated receptors
F2RL3	F2R like thrombin or trypsin receptor 3	Proteinase-activated receptors
QRFPR	pyroglutamylated RFamide peptide receptor	QRFP receptor
RXFP1	relaxin family peptide receptor 1	Relaxin family peptide receptors
RXFP2	relaxin family peptide receptor 2	Relaxin family peptide receptors
RXFP3	relaxin family peptide receptor 3	Relaxin family peptide receptors
RXFP4	relaxin family peptide/INSL5 receptor 4	Relaxin family peptide receptors
SSTR1	somatostatin receptor 1	Somatostatin receptors
SSTR2	somatostatin receptor 2	Somatostatin receptors
SSTR3	somatostatin receptor 3	Somatostatin receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
SSTR5	somatostatin receptor 5	Somatostatin receptors
SUCNR1	succinate receptor 1	Succinate receptor
TACR1	tachykinin receptor 1	Tachykinin receptors
TACR2	tachykinin receptor 2	Tachykinin receptors
TACR3	tachykinin receptor 3	Tachykinin receptors
TRHR	thyrotropin releasing hormone receptor	Thyrotropin-releasing hormone receptors
TAAR1	trace amine associated receptor 1	Trace amine receptor
UTS2R	urotensin 2 receptor	Urotensin receptor
AVPR1A	arginine vasopressin receptor 1A	Vasopressin and oxytocin receptors
AVPR1B	arginine vasopressin receptor 1B	Vasopressin and oxytocin receptors
AVPR2	arginine vasopressin receptor 2	Vasopressin and oxytocin receptors
OXTR	oxytocin receptor	Vasopressin and oxytocin receptors
ADCYAP1R1	ADCYAP receptor type I	VIP and PACAP receptors
VIPR1	vasoactive intestinal peptide receptor 1	VIP and PACAP receptors
VIPR2	vasoactive intestinal peptide receptor 2	VIP and PACAP receptors
AGTR2	angiotensin II receptor type 2	Orphan receptors
GPRC6A	G protein-coupled receptor class C group 6 member A	Orphan receptors
GPR18	G protein-coupled receptor 18	Orphan receptors
GPR1	G protein-coupled receptor 1	Orphan receptors
ACKR4	atypical chemokine receptor 4	Orphan receptors
CCRL2	C-C motif chemokine receptor like 2	Orphan receptors
ACKR1	atypical chemokine receptor 1 (Duffy blood group)	Orphan receptors
ACKR2	atypical chemokine receptor 2	Orphan receptors
ACKR3	atypical chemokine receptor 3	Orphan receptors
GPER1	G protein-coupled estrogen receptor 1	Orphan receptors
GPR151	G protein-coupled receptor 151	Orphan receptors
TAAR2	trace amine associated receptor 2	Orphan receptors
TAAR5	trace amine associated receptor 5	Orphan receptors
TAAR6	trace amine associated receptor 6	Orphan receptors
TAAR8	trace amine associated receptor 8	Orphan receptors
TAAR9	trace amine associated receptor 9	Orphan receptors
GPR4	G protein-coupled receptor 4	Orphan receptors
GPR65	G protein-coupled receptor 65	Orphan receptors
GPR68	G protein-coupled receptor 68	Orphan receptors
GPR132	G protein-coupled receptor 132	Orphan receptors
GPR3	G protein-coupled receptor 3	Orphan receptors
GPR6	G protein-coupled receptor 6	Orphan receptors
GPR12	G protein-coupled receptor 12	Orphan receptors
GPR15	G protein-coupled receptor 15	Orphan receptors
GPR17	G protein-coupled receptor 17	Orphan receptors
GPR19	G protein-coupled receptor 19	Orphan receptors
GPR20	G protein-coupled receptor 20	Orphan receptors
GPR21	G protein-coupled receptor 21	Orphan receptors
GPR22	G protein-coupled receptor 22	Orphan receptors
GPR25	G protein-coupled receptor 25	Orphan receptors
GPR26	G protein-coupled receptor 26	Orphan receptors
GPR27	G protein-coupled receptor 27	Orphan receptors
GPR31	G protein-coupled receptor 31	Orphan receptors
GPR32	G protein-coupled receptor 32	Orphan receptors
GPR34	G protein-coupled receptor 34	Lysophospholipid (LPS) receptors
GPR35	G protein-coupled receptor 35	Orphan receptors
GPR37	G protein-coupled receptor 37	Orphan receptors
GPR37L1	G protein-coupled receptor 37 like 1	Orphan receptors
GPR39	G protein-coupled receptor 39	Orphan receptors
GPR45	G protein-coupled receptor 45	Orphan receptors
GPR50	G protein-coupled receptor 50	Orphan receptors
GPR52	G protein-coupled receptor 52	Orphan receptors
GPR61	G protein-coupled receptor 61	Orphan receptors
GPR62	G protein-coupled receptor 62	Orphan receptors
GPR63	G protein-coupled receptor 63	Orphan receptors
GPR75	G protein-coupled receptor 75	Orphan receptors
GPR78	G protein-coupled receptor 78	Orphan receptors
GPR82	G protein-coupled receptor 82	Orphan receptors
GPR83	G protein-coupled receptor 83	Orphan receptors
GPR85	G protein-coupled receptor 85	Orphan receptors
GPR87	G protein-coupled receptor 87	Orphan receptors
GPR88	G protein-coupled receptor 88	Orphan receptors
GPR101	G protein-coupled receptor 101	Orphan receptors
GPR135	G protein-coupled receptor 135	Orphan receptors
GPR139	G protein-coupled receptor 139	Orphan receptors
GPR141	G protein-coupled receptor 141	Orphan receptors
GPR142	G protein-coupled receptor 142	Orphan receptors
GPR146	G protein-coupled receptor 146	Orphan receptors
GPR148	G protein-coupled receptor 148	Orphan receptors
GPR149	G protein-coupled receptor 149	Orphan receptors
GPR150	G protein-coupled receptor 150	Orphan receptors
GPR152	G protein-coupled receptor 152	Orphan receptors
GPR153	G protein-coupled receptor 153	Orphan receptors
GPR160	G protein-coupled receptor 160	Orphan receptors
GPR161	G protein-coupled receptor 161	Orphan receptors
GPR162	G protein-coupled receptor 162	Orphan receptors
GPR171	G protein-coupled receptor 171	Orphan receptors
GPR173	G protein-coupled receptor 173	Orphan receptors
GPR174	G protein-coupled receptor 174	Lysophospholipid (LPS) receptors
GPR176	G protein-coupled receptor 176	Orphan receptors
GPR182	G protein-coupled receptor 182	Orphan receptors
LGR4	leucine rich repeat containing G protein-coupled receptor 4	Orphan receptors
LGR5	leucine rich repeat containing G protein-coupled receptor 5	Orphan receptors
LGR6	leucine rich repeat containing G protein-coupled receptor 6	Orphan receptors
MAS1	MAS1 proto-oncogene, G protein-coupled receptor	Orphan receptors
MAS1L	MAS1 proto-oncogene like, G protein-coupled receptor	Orphan receptors
MRGPRD	MAS related GPR family member D	Orphan receptors
MRGPRE	MAS related GPR family member E	Orphan receptors
MRGPRF	MAS related GPR family member F	Orphan receptors
MRGPRG	MAS related GPR family member G	Orphan receptors
MRGPRX1	MAS related GPR family member X1	Orphan receptors
MRGPRX2	MAS related GPR family member X2	Orphan receptors
MRGPRX3	MAS related GPR family member X3	Orphan receptors
MRGPRX4	MAS related GPR family member X4	Orphan receptors
GPR156	G protein-coupled receptor 156	Orphan receptors
GPR158	G protein-coupled receptor 158	Orphan receptors
GPRC5A	G protein-coupled receptor class C group 5 member A	Orphan receptors
GPRC5B	G protein-coupled receptor class C group 5 member B	Orphan receptors
GPRC5C	G protein-coupled receptor class C group 5 member C	Orphan receptors
GPRC5D	G protein-coupled receptor class C group 5 member D	Orphan receptors
GPR107	G protein-coupled receptor 107	Orphan receptors
GPR137	G protein-coupled receptor 137	Orphan receptors
GPR143	G protein-coupled receptor 143	Orphan receptors
GPR157	G protein-coupled receptor 157	Orphan receptors
TPRA1	transmembrane protein adipocyte associated 1	Orphan receptors
P2RY8	P2Y receptor family member 8	Orphan receptors

Symbol	HGNC name	Family
CHRM2	cholinergic receptor muscarinic 2	Acetylcholine receptors (muscarinic)
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADORA2B	adenosine A2b receptor	Adenosine receptors
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
BRS3	bombesin receptor subtype 3	Bombesin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR4	C-C motif chemokine receptor 4	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CCR8	C-C motif chemokine receptor 8	Chemokine receptors
CCR9	C-C motif chemokine receptor 9	Chemokine receptors
CXCR1	C-X-C motif chemokine receptor 1	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR5	C-X-C motif chemokine receptor 5	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
C5AR1	complement C5a receptor 1	Complement peptide receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
GPR183	G protein-coupled receptor 183	Steroid receptors
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
HRH1	histamine receptor H1	Histamine receptors
LTB4R	leukotriene B4 receptor	Leukotriene receptors
CYSLTR1	cysteinyl leukotriene receptor 1	Leukotriene receptors
CYSLTR2	cysteinyl leukotriene receptor 2	Leukotriene receptors
PTAFR	platelet activating factor receptor	Platelet-activating factor receptor
MC2R	melanocortin 2 receptor	Melanocortin receptors
OPRM1	opioid receptor mu 1	Opioid receptors
P2RY12	purinergic receptor P2Y12	P2Y receptors
PTGDR2	prostaglandin D2 receptor 2	Prostanoid receptors
PTGER2	prostaglandin E receptor 2	Prostanoid receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
F2RL1	F2R like trypsin receptor 1	Proteinase-activated receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
ADCYAP1R1	ADCYAP receptor type I	VIP and PACAP receptors

Symbol	HGNC name	Family
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
BRS3	bombesin receptor subtype 3	Bombesin receptors
GRPR	gastrin releasing peptide receptor	Bombesin receptors
NMBR	neuromedin B receptor	Bombesin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR4	C-C motif chemokine receptor 4	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CCKAR	cholecystokinin A receptor	Cholecystokinin receptors
CCKBR	cholecystokinin B receptor	Cholecystokinin receptors
CRHR1	corticotropin releasing hormone receptor 1	Corticotropin-releasing factor receptors
DRD2	dopamine receptor D2	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
GHSR	growth hormone secretagogue receptor	Ghrelin receptor
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
FSHR	follicle stimulating hormone receptor	Glycoprotein hormone receptors
LHCGR	luteinizing hormone/choriogonadotropin receptor	Glycoprotein hormone receptors
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
GNRHR	gonadotropin releasing hormone receptor	Gonadotrophin-releasing hormone receptors
HRH4	histamine receptor H4	Histamine receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
CYSLTR2	cysteinyl leukotriene receptor 2	Leukotriene receptors
LPAR1	lysophosphatidic acid receptor 1	Lysophospholipid (LPA) receptors
LPAR3	lysophosphatidic acid receptor 3	Lysophospholipid (LPA) receptors
S1PR1	sphingosine-1-phosphate receptor 1	Lysophospholipid (S1P) receptors
MC1R	melanocortin 1 receptor	Melanocortin receptors
GRM1	glutamate metabotropic receptor 1	Metabotropic glutamate receptors
NTSR1	neurotensin receptor 1	Neurotensin receptors
PTH1R	parathyroid hormone 1 receptor	Parathyroid hormone receptors
PTGER1	prostaglandin E receptor 1	Prostanoid receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
F2RL1	F2R like trypsin receptor 1	Proteinase-activated receptors
SSTR1	somatostatin receptor 1	Somatostatin receptors
SSTR2	somatostatin receptor 2	Somatostatin receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors

Symbol	HGNC name	Family
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
BRS3	bombesin receptor subtype 3	Bombesin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR4	C-C motif chemokine receptor 4	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CCR8	C-C motif chemokine receptor 8	Chemokine receptors
CCR9	C-C motif chemokine receptor 9	Chemokine receptors
CCR10	C-C motif chemokine receptor 10	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR5	C-X-C motif chemokine receptor 5	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
C5AR1	complement C5a receptor 1	Complement peptide receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
GPR183	G protein-coupled receptor 183	Steroid receptors
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
CYSLTR1	cysteinyl leukotriene receptor 1	Leukotriene receptors
PTAFR	platelet activating factor receptor	Platelet-activating factor receptor
S1PR1	sphingosine-1-phosphate receptor 1	Lysophospholipid (S1P) receptors
S1PR2	sphingosine-1-phosphate receptor 2	Lysophospholipid (S1P) receptors
NPY5R	neuropeptide Y receptor Y5	Neuropeptide Y receptors
OPRK1	opioid receptor kappa 1	Opioid receptors
OPRM1	opioid receptor mu 1	Opioid receptors
P2RY12	purinergic receptor P2Y12	P2Y receptors
PTH1R	parathyroid hormone 1 receptor	Parathyroid hormone receptors
PTGDR	prostaglandin D2 receptor	Prostanoid receptors
PTGDR2	prostaglandin D2 receptor 2	Prostanoid receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
F2RL3	F2R like thrombin or trypsin receptor 3	Proteinase-activated receptors
RXFP1	relaxin family peptide receptor 1	Relaxin family peptide receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
ADCYAP1R1	ADCYAP receptor type I	VIP and PACAP receptors
VIPR1	vasoactive intestinal peptide receptor 1	VIP and PACAP receptors

Symbol	HGNC name	Family
HTR2A	5-hydroxytryptamine receptor 2A	5-Hydroxytryptamine receptors
HTR2C	5-hydroxytryptamine receptor 2C	5-Hydroxytryptamine receptors
CHRM2	cholinergic receptor muscarinic 2	Acetylcholine receptors (muscarinic)
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRB1	adrenoceptor beta 1	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
ADRB3	adrenoceptor beta 3	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
BRS3	bombesin receptor subtype 3	Bombesin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CCKAR	cholecystokinin A receptor	Cholecystokinin receptors
CCKBR	cholecystokinin B receptor	Cholecystokinin receptors
DRD2	dopamine receptor D2	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
FFAR1	free fatty acid receptor 1	Free fatty acid receptors
GHSR	growth hormone secretagogue receptor	Ghrelin receptor
GHRHR	growth hormone releasing hormone receptor	Glucagon receptor family
GIPR	gastric inhibitory polypeptide receptor	Glucagon receptor family
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
GCGR	glucagon receptor	Glucagon receptor family
FSHR	follicle stimulating hormone receptor	Glycoprotein hormone receptors
LHCGR	luteinizing hormone/choriogonadotropin receptor	Glycoprotein hormone receptors
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
GNRHR	gonadotropin releasing hormone receptor	Gonadotrophin-releasing hormone receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
S1PR2	sphingosine-1-phosphate receptor 2	Lysophospholipid (S1P) receptors
MC1R	melanocortin 1 receptor	Melanocortin receptors
MC2R	melanocortin 2 receptor	Melanocortin receptors
MC4R	melanocortin 4 receptor	Melanocortin receptors
MTNR1B	melatonin receptor 1B	Melatonin receptors
NPY1R	neuropeptide Y receptor Y1	Neuropeptide Y receptors
NPY2R	neuropeptide Y receptor Y2	Neuropeptide Y receptors
NPY5R	neuropeptide Y receptor Y5	Neuropeptide Y receptors
OPRM1	opioid receptor mu 1	Opioid receptors
PTH1R	parathyroid hormone 1 receptor	Parathyroid hormone receptors
PROKR2	prokineticin receptor 2	Prokineticin receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
SSTR1	somatostatin receptor 1	Somatostatin receptors
SSTR2	somatostatin receptor 2	Somatostatin receptors
TACR3	tachykinin receptor 3	Tachykinin receptors
TRHR	thyrotropin releasing hormone receptor	Thyrotropin-releasing hormone receptors
AVPR2	arginine vasopressin receptor 2	Vasopressin and oxytocin receptors

Symbol	HGNC name	Family
HTR1A	5-hydroxytryptamine receptor 1A	5-Hydroxytryptamine receptors
HTR1B	5-hydroxytryptamine receptor 1B	5-Hydroxytryptamine receptors
HTR2A	5-hydroxytryptamine receptor 2A	5-Hydroxytryptamine receptors
HTR2C	5-hydroxytryptamine receptor 2C	5-Hydroxytryptamine receptors
HTR5A	5-hydroxytryptamine receptor 5A	5-Hydroxytryptamine receptors
HTR6	5-hydroxytryptamine receptor 6	5-Hydroxytryptamine receptors
HTR7	5-hydroxytryptamine receptor 7	5-Hydroxytryptamine receptors
CHRM1	cholinergic receptor muscarinic 1	Acetylcholine receptors (muscarinic)
CHRM2	cholinergic receptor muscarinic 2	Acetylcholine receptors (muscarinic)
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
CHRM4	cholinergic receptor muscarinic 4	Acetylcholine receptors (muscarinic)
CHRM5	cholinergic receptor muscarinic 5	Acetylcholine receptors (muscarinic)
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADRA2A	adrenoceptor alpha 2A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB1	adrenoceptor beta 1	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
GRPR	gastrin releasing peptide receptor	Bombesin receptors
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCKAR	cholecystokinin A receptor	Cholecystokinin receptors
CCKBR	cholecystokinin B receptor	Cholecystokinin receptors
CRHR1	corticotropin releasing hormone receptor 1	Corticotropin-releasing factor receptors
CRHR2	corticotropin releasing hormone receptor 2	Corticotropin-releasing factor receptors
DRD1	dopamine receptor D1	Dopamine receptors
DRD2	dopamine receptor D2	Dopamine receptors
DRD3	dopamine receptor D3	Dopamine receptors
DRD4	dopamine receptor D4	Dopamine receptors
DRD5	dopamine receptor D5	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
GABBR1/2	gamma-aminobutyric acid type B receptor subunits 1/2	GABA_B receptors
HRH1	histamine receptor H1	Histamine receptors
HRH2	histamine receptor H2	Histamine receptors
HRH3	histamine receptor H3	Histamine receptors
GRM2	glutamate metabotropic receptor 2	Metabotropic glutamate receptors
GRM8	glutamate metabotropic receptor 8	Metabotropic glutamate receptors
NPSR1	neuropeptide S receptor 1	Neuropeptide S receptor
NPY1R	neuropeptide Y receptor Y1	Neuropeptide Y receptors
NPY2R	neuropeptide Y receptor Y2	Neuropeptide Y receptors
NTSR1	neurotensin receptor 1	Neurotensin receptors
OPRD1	opioid receptor delta 1	Opioid receptors
OPRK1	opioid receptor kappa 1	Opioid receptors
OPRM1	opioid receptor mu 1	Opioid receptors
OPRL1	opioid related nociceptin receptor 1	Opioid receptors
HCRTR1	hypocretin receptor 1	Orexin receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
AVPR1A	arginine vasopressin receptor 1A	Vasopressin and oxytocin receptors
OXTR	oxytocin receptor	Vasopressin and oxytocin receptors
ADCYAP1R1	ADCYAP receptor type I	VIP and PACAP receptors

Symbol	HGNC name	Family
HTR1A	5-hydroxytryptamine receptor 1A	5-Hydroxytryptamine receptors
HTR1B	5-hydroxytryptamine receptor 1B	5-Hydroxytryptamine receptors
HTR2A	5-hydroxytryptamine receptor 2A	5-Hydroxytryptamine receptors
HTR2C	5-hydroxytryptamine receptor 2C	5-Hydroxytryptamine receptors
HTR7	5-hydroxytryptamine receptor 7	5-Hydroxytryptamine receptors
CHRM1	cholinergic receptor muscarinic 1	Acetylcholine receptors (muscarinic)
CHRM2	cholinergic receptor muscarinic 2	Acetylcholine receptors (muscarinic)
CHRM4	cholinergic receptor muscarinic 4	Acetylcholine receptors (muscarinic)
ADORA1	adenosine A1 receptor	Adenosine receptors
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADRA1B	adrenoceptor alpha 1B	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CCR9	C-C motif chemokine receptor 9	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
CCKBR	cholecystokinin B receptor	Cholecystokinin receptors
CRHR1	corticotropin releasing hormone receptor 1	Corticotropin-releasing factor receptors
DRD1	dopamine receptor D1	Dopamine receptors
DRD2	dopamine receptor D2	Dopamine receptors
DRD3	dopamine receptor D3	Dopamine receptors
DRD4	dopamine receptor D4	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
GABBR1/2	gamma-aminobutyric acid type B receptor subunits 1/2	GABA_B receptors
HRH3	histamine receptor H3	Histamine receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
MC1R	melanocortin 1 receptor	Melanocortin receptors
GRM1	glutamate metabotropic receptor 1	Metabotropic glutamate receptors
NPY1R	neuropeptide Y receptor Y1	Neuropeptide Y receptors
NPY2R	neuropeptide Y receptor Y2	Neuropeptide Y receptors
OPRK1	opioid receptor kappa 1	Opioid receptors
OPRM1	opioid receptor mu 1	Opioid receptors
PROKR2	prokineticin receptor 2	Prokineticin receptors
PTGER1	prostaglandin E receptor 1	Prostanoid receptors
SSTR1	somatostatin receptor 1	Somatostatin receptors
SSTR2	somatostatin receptor 2	Somatostatin receptors
SSTR3	somatostatin receptor 3	Somatostatin receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
SSTR5	somatostatin receptor 5	Somatostatin receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
TACR3	tachykinin receptor 3	Tachykinin receptors

Symbol	HGNC name	Family
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
BRS3	bombesin receptor subtype 3	Bombesin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR5	C-X-C motif chemokine receptor 5	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
DRD5	dopamine receptor D5	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
FFAR4	free fatty acid receptor 4	Free fatty acid receptors
GHSR	growth hormone secretagogue receptor	Ghrelin receptor
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
HCAR2	hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
CYSLTR2	cysteinyl leukotriene receptor 2	Leukotriene receptors
OXER1	oxoeicosanoid receptor 1	Leukotriene receptors
PTAFR	platelet activating factor receptor	Platelet-activating factor receptor
LPAR3	lysophosphatidic acid receptor 3	Lysophospholipid (LPA) receptors
LPAR6	lysophosphatidic acid receptor 6	Lysophospholipid (LPA) receptors
MC1R	melanocortin 1 receptor	Melanocortin receptors
MTNR1A	melatonin receptor 1A	Melatonin receptors
GRM1	glutamate metabotropic receptor 1	Metabotropic glutamate receptors
GRM6	glutamate metabotropic receptor 6	Metabotropic glutamate receptors
PTH1R	parathyroid hormone 1 receptor	Parathyroid hormone receptors
PROKR2	prokineticin receptor 2	Prokineticin receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
PTGFR	prostaglandin F receptor	Prostanoid receptors
F2RL1	F2R like trypsin receptor 1	Proteinase-activated receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
SUCNR1	succinate receptor 1	Succinate receptor
TACR3	tachykinin receptor 3	Tachykinin receptors
VIPR2	vasoactive intestinal peptide receptor 2	VIP and PACAP receptors

Symbol	HGNC name	Family
HTR1B	5-hydroxytryptamine receptor 1B	5-Hydroxytryptamine receptors
HTR2B	5-hydroxytryptamine receptor 2B	5-Hydroxytryptamine receptors
HTR4	5-hydroxytryptamine receptor 4	5-Hydroxytryptamine receptors
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADORA1	adenosine A1 receptor	Adenosine receptors
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA1B	adrenoceptor alpha 1B	Adrenoceptors
ADRA2A	adrenoceptor alpha 2A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRA2C	adrenoceptor alpha 2C	Adrenoceptors
ADRB1	adrenoceptor beta 1	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
ADRB3	adrenoceptor beta 3	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
APLNR	apelin receptor	Apelin receptor
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
CRHR2	corticotropin releasing hormone receptor 2	Corticotropin-releasing factor receptors
DRD2	dopamine receptor D2	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
GHSR	growth hormone secretagogue receptor	Ghrelin receptor
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
HRH1	histamine receptor H1	Histamine receptors
HRH3	histamine receptor H3	Histamine receptors
PTAFR	platelet activating factor receptor	Platelet-activating factor receptor
OPRD1	opioid receptor delta 1	Opioid receptors
OPRK1	opioid receptor kappa 1	Opioid receptors
OPRM1	opioid receptor mu 1	Opioid receptors
P2RY1	purinergic receptor P2Y1	P2Y receptors
P2RY12	purinergic receptor P2Y12	P2Y receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
UTS2R	urotensin 2 receptor	Urotensin receptor
AVPR1A	arginine vasopressin receptor 1A	Vasopressin and oxytocin receptors
AVPR2	arginine vasopressin receptor 2	Vasopressin and oxytocin receptors

Symbol	HGNC name	Family
HTR2A	5-hydroxytryptamine receptor 2A	5-Hydroxytryptamine receptors
HTR2B	5-hydroxytryptamine receptor 2B	5-Hydroxytryptamine receptors
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADORA1	adenosine A1 receptor	Adenosine receptors
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
BRS3	bombesin receptor subtype 3	Bombesin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR4	C-C motif chemokine receptor 4	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR8	C-C motif chemokine receptor 8	Chemokine receptors
CCR9	C-C motif chemokine receptor 9	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
C3AR1	complement C3a receptor 1	Complement peptide receptors
C5AR1	complement C5a receptor 1	Complement peptide receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
HRH1	histamine receptor H1	Histamine receptors
CYSLTR1	cysteinyl leukotriene receptor 1	Leukotriene receptors
CYSLTR2	cysteinyl leukotriene receptor 2	Leukotriene receptors
PTAFR	platelet activating factor receptor	Platelet-activating factor receptor
NPSR1	neuropeptide S receptor 1	Neuropeptide S receptor
OPRM1	opioid receptor mu 1	Opioid receptors
P2RY12	purinergic receptor P2Y12	P2Y receptors
PTH1R	parathyroid hormone 1 receptor	Parathyroid hormone receptors
PTGDR2	prostaglandin D2 receptor 2	Prostanoid receptors
PTGER2	prostaglandin E receptor 2	Prostanoid receptors
PTGFR	prostaglandin F receptor	Prostanoid receptors
PTGIR	prostaglandin I2 receptor	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
F2RL1	F2R like trypsin receptor 1	Proteinase-activated receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
TACR2	tachykinin receptor 2	Tachykinin receptors
OXTR	oxytocin receptor	Vasopressin and oxytocin receptors
ADCYAP1R1	ADCYAP receptor type I	VIP and PACAP receptors

Symbol	HGNC name	Family
HTR1A	5-hydroxytryptamine receptor 1A	5-Hydroxytryptamine receptors
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADORA3	adenosine A3 receptor	Adenosine receptors
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB1	adrenoceptor beta 1	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
GPBAR1	G protein-coupled bile acid receptor 1	Bile acid receptor
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR4	C-C motif chemokine receptor 4	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CXCR1	C-X-C motif chemokine receptor 1	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR5	C-X-C motif chemokine receptor 5	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
CCKAR	cholecystokinin A receptor	Cholecystokinin receptors
CCKBR	cholecystokinin B receptor	Cholecystokinin receptors
CRHR2	corticotropin releasing hormone receptor 2	Corticotropin-releasing factor receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
FPR2	formyl peptide receptor 2	Formylpeptide receptors
GHSR	growth hormone secretagogue receptor	Ghrelin receptor
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
HRH2	histamine receptor H2	Histamine receptors
HRH4	histamine receptor H4	Histamine receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
LTB4R	leukotriene B4 receptor	Leukotriene receptors
PTAFR	platelet activating factor receptor	Platelet-activating factor receptor
LPAR1	lysophosphatidic acid receptor 1	Lysophospholipid (LPA) receptors
OPRM1	opioid receptor mu 1	Opioid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
F2RL1	F2R like trypsin receptor 1	Proteinase-activated receptors
F2RL3	F2R like thrombin or trypsin receptor 3	Proteinase-activated receptors
SSTR1	somatostatin receptor 1	Somatostatin receptors
SSTR2	somatostatin receptor 2	Somatostatin receptors
SSTR3	somatostatin receptor 3	Somatostatin receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
VIPR1	vasoactive intestinal peptide receptor 1	VIP and PACAP receptors

Symbol	HGNC name	Family
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA2A	adrenoceptor alpha 2A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
BRS3	bombesin receptor subtype 3	Bombesin receptors
NMBR	neuromedin B receptor	Bombesin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR4	C-C motif chemokine receptor 4	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR5	C-X-C motif chemokine receptor 5	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
CRHR1	corticotropin releasing hormone receptor 1	Corticotropin-releasing factor receptors
DRD2	dopamine receptor D2	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
LHCGR	luteinizing hormone/choriogonadotropin receptor	Glycoprotein hormone receptors
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
HRH1	histamine receptor H1	Histamine receptors
HRH4	histamine receptor H4	Histamine receptors
HCAR2	hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptors
HCAR3	hydroxycarboxylic acid receptor 3	Hydroxycarboxylic acid receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
LPAR1	lysophosphatidic acid receptor 1	Lysophospholipid (LPA) receptors
LPAR6	lysophosphatidic acid receptor 6	Lysophospholipid (LPA) receptors
MC1R	melanocortin 1 receptor	Melanocortin receptors
GRM1	glutamate metabotropic receptor 1	Metabotropic glutamate receptors
OPRM1	opioid receptor mu 1	Opioid receptors
P2RY12	purinergic receptor P2Y12	P2Y receptors
PROKR2	prokineticin receptor 2	Prokineticin receptors
PTGER1	prostaglandin E receptor 1	Prostanoid receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
F2RL1	F2R like trypsin receptor 1	Proteinase-activated receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
UTS2R	urotensin 2 receptor	Urotensin receptor

Symbol	HGNC name	Family
HTR7	5-hydroxytryptamine receptor 7	5-Hydroxytryptamine receptors
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADORA2A	adenosine A2a receptor	Adenosine receptors
ADRA2A	adrenoceptor alpha 2A	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CCR1	C-C motif chemokine receptor 1	Chemokine receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CCR7	C-C motif chemokine receptor 7	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR5	C-X-C motif chemokine receptor 5	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
C5AR1	complement C5a receptor 1	Complement peptide receptors
CRHR1	corticotropin releasing hormone receptor 1	Corticotropin-releasing factor receptors
DRD2	dopamine receptor D2	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
GABBR1/2	gamma-aminobutyric acid type B receptor subunits 1/2	GABA_B receptors
GHSR	growth hormone secretagogue receptor	Ghrelin receptor
GHRHR	growth hormone releasing hormone receptor	Glucagon receptor family
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
FSHR	follicle stimulating hormone receptor	Glycoprotein hormone receptors
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
GNRHR	gonadotropin releasing hormone receptor	Gonadotrophin-releasing hormone receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
LPAR1	lysophosphatidic acid receptor 1	Lysophospholipid (LPA) receptors
MC1R	melanocortin 1 receptor	Melanocortin receptors
MC2R	melanocortin 2 receptor	Melanocortin receptors
GRM1	glutamate metabotropic receptor 1	Metabotropic glutamate receptors
PTH1R	parathyroid hormone 1 receptor	Parathyroid hormone receptors
PTH2R	parathyroid hormone 2 receptor	Parathyroid hormone receptors
PROKR2	prokineticin receptor 2	Prokineticin receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
F2RL1	F2R like trypsin receptor 1	Proteinase-activated receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
TACR1	tachykinin receptor 1	Tachykinin receptors
TACR3	tachykinin receptor 3	Tachykinin receptors
TRHR	thyrotropin releasing hormone receptor	Thyrotropin-releasing hormone receptors
AVPR2	arginine vasopressin receptor 2	Vasopressin and oxytocin receptors

Symbol	HGNC name	Family
CHRM2	cholinergic receptor muscarinic 2	Acetylcholine receptors (muscarinic)
CHRM3	cholinergic receptor muscarinic 3	Acetylcholine receptors (muscarinic)
ADRA1A	adrenoceptor alpha 1A	Adrenoceptors
ADRA2B	adrenoceptor alpha 2B	Adrenoceptors
ADRB2	adrenoceptor beta 2	Adrenoceptors
AGTR1	angiotensin II receptor type 1	Angiotensin receptors
BRS3	bombesin receptor subtype 3	Bombesin receptors
GRPR	gastrin releasing peptide receptor	Bombesin receptors
CALCR	calcitonin receptor	Calcitonin receptors
CASR	calcium sensing receptor	Calcium-sensing receptor
CNR1	cannabinoid receptor 1	Cannabinoid receptors
CMKLR1	chemerin chemokine-like receptor 1	Chemerin receptors
CCR2	C-C motif chemokine receptor 2	Chemokine receptors
CCR5	C-C motif chemokine receptor 5 (gene/pseudogene)	Chemokine receptors
CCR6	C-C motif chemokine receptor 6	Chemokine receptors
CXCR2	C-X-C motif chemokine receptor 2	Chemokine receptors
CXCR3	C-X-C motif chemokine receptor 3	Chemokine receptors
CXCR4	C-X-C motif chemokine receptor 4	Chemokine receptors
CXCR6	C-X-C motif chemokine receptor 6	Chemokine receptors
CX3CR1	C-X3-C motif chemokine receptor 1	Chemokine receptors
DRD1	dopamine receptor D1	Dopamine receptors
DRD2	dopamine receptor D2	Dopamine receptors
EDNRA	endothelin receptor type A	Endothelin receptors
EDNRB	endothelin receptor type B	Endothelin receptors
GLP1R	glucagon like peptide 1 receptor	Glucagon receptor family
FSHR	follicle stimulating hormone receptor	Glycoprotein hormone receptors
LHCGR	luteinizing hormone/choriogonadotropin receptor	Glycoprotein hormone receptors
TSHR	thyroid stimulating hormone receptor	Glycoprotein hormone receptors
GNRHR	gonadotropin releasing hormone receptor	Gonadotrophin-releasing hormone receptors
KISS1R	KISS1 receptor	Kisspeptin receptor
PTAFR	platelet activating factor receptor	Platelet-activating factor receptor
LPAR1	lysophosphatidic acid receptor 1	Lysophospholipid (LPA) receptors
MC2R	melanocortin 2 receptor	Melanocortin receptors
MTNR1B	melatonin receptor 1B	Melatonin receptors
PTH1R	parathyroid hormone 1 receptor	Parathyroid hormone receptors
PROKR2	prokineticin receptor 2	Prokineticin receptors
PTGER1	prostaglandin E receptor 1	Prostanoid receptors
PTGER2	prostaglandin E receptor 2	Prostanoid receptors
PTGER4	prostaglandin E receptor 4	Prostanoid receptors
PTGFR	prostaglandin F receptor	Prostanoid receptors
F2R	coagulation factor II thrombin receptor	Proteinase-activated receptors
RXFP1	relaxin family peptide receptor 1	Relaxin family peptide receptors
RXFP2	relaxin family peptide receptor 2	Relaxin family peptide receptors
SSTR4	somatostatin receptor 4	Somatostatin receptors
TACR3	tachykinin receptor 3	Tachykinin receptors
UTS2R	urotensin 2 receptor	Urotensin receptor
AVPR1A	arginine vasopressin receptor 1A	Vasopressin and oxytocin receptors
AVPR2	arginine vasopressin receptor 2	Vasopressin and oxytocin receptors

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