Human CXCR4

Figure. Concentration-dependent activation of CXCR4 by cXCL12a

Reporter cells were transfected with either the expression plasmid for human C-X-C motif chemokine receptor 4 (CXCR4) or the mock plasmid and treated with various concentrations of cXCL12a. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 5.4 nM.

Nomenclature
C-X-C motif chemokine receptor 4
Available assay modes
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Panels
à la carte | Cardiology | Dermatology | Endocrinology/Metabolism | Gastrointestinal | Hematology | Human non-orphan GPCRs | Immunology/Infection | Musculoskeletal | Neurology | Oncology | Ophthalmology | Respiratory | Urology/Reproduction

CXCR4 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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