Human CCR5

Figure. Concentration-dependent activation of CCR5 by CCL4

Reporter cells were transfected with either the expression plasmid for human C-C motif chemokine receptor 5 (CCR5) or the mock plasmid and treated with various concentrations of CCL4. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 7.1 nM.

C-C motif chemokine receptor 5
Available assay modes
à la carte | Cardiology | Dermatology | Endocrinology/Metabolism | Gastrointestinal | Hematology | Human non-orphan GPCRs | Immunology/Infection | Musculoskeletal | Neurology | Oncology | Ophthalmology | Respiratory | Urology/Reproduction

CCR5 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

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