Human CCR7

Figure. Concentration-dependent activation of CCR7 by CCL21

Reporter cells were transfected with either the expression plasmid for human C-C motif chemokine receptor 7 (CCR7) or the mock plasmid and treated with various concentrations of CCL21. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 15 nM.

C-C motif chemokine receptor 7
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
à la carte, Immunology/Infection, Oncology, Hematology, Neurology, Ophthalmology, Gastrointestinal, Dermatology, Musculoskeletal, Human non-orphan GPCRs

CCR7 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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