Figure. Concentration-dependent activation of CCR8 by CCL1. Reporter cells were transfected with either the expression plasmid for C-C motif chemo­kine receptor 8 (CCR8) or the mock plasmid and treated with various concentrations of C-C motif chemo­kine ligand 1 (CCL1). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 6.8 nM.