Human F2R

Figure. Concentration-dependent activation of F2R by TFLLR‐NH2

Reporter cells were transfected with either the expression plasmid for human coagulation factor ⅠⅠ thrombin receptor (F2R) or the mock plasmid and treated with various concentrations of TFLLR‐NH2. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 180 nM.

Nomenclature
coagulation factor ⅠⅠ thrombin receptor
Available assay modes
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Panels
à la carte | Cardiology | Dermatology | Gastrointestinal | Hematology | Human non-orphan GPCRs | Immunology/Infection | Musculoskeletal | Oncology | Respiratory | Urology/Reproduction

F2R orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

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