Figure. Concentration-dependent activation of EDNRA by ET‐1

Reporter cells were transfected with either the expression plasmid for human endothelin receptor type A (EDNRA) or the mock plasmid and treated with various concentrations of ET‐1. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 5.5 nM.

endothelin receptor type A
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EDNRA orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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