endothelin receptor type B (EDNRB)

Human EDNRB

Figure. Concentration-dependent activation of EDNRB by ET‐1

Reporter cells were transfected with either the expression plasmid for human endothelin receptor type B (EDNRB) or the mock plasmid and treated with various concentrations of ET‐1. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 5.0 nM.

Description

Nomenclature: endothelin receptor type B
Available assay modes: Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels: à la carte, Immunology/Infection, Oncology, Hematology, Endocrinology/Metabolism, Neurology, Ophthalmology, Cardiology, Respiratory, Gastrointestinal, Dermatology, Musculoskeletal, Urology/Reproduction, Human non-orphan GPCRs

Endothelin receptors
Endothelin receptors are activated by the endogenous 21 amino-acid peptides endothelins 1-3 (endothelin-1, endothelin-2 and endothelin-3).

Excerpt from IUPHAR/BPS Guide to Pharmacology

Related Receptors


Human	EDNRA endothelin receptor type A
Human	EDNRB endothelin receptor type B
Mouse	Ednra endothelin receptor type A
Mouse	Ednrb endothelin receptor type B