Human P2RY12

Figure. Concentration-dependent activation of P2RY12 by ADP

Reporter cells were transfected with either the expression plasmid for human purinergic receptor P2Y12 (P2RY12) or the mock plasmid and treated with various concentrations of ADP. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 3.0 µM.

purinergic receptor P2Y12
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
à la carte, Immunology/Infection, Hematology, Cardiology, Respiratory, Dermatology, Human non-orphan GPCRs

P2RY12 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors