Description
Figure. Concentration-dependent activation of P2RY6 by UDP. Reporter cells were transfected with either the expression plasmid for pyrimidinergic receptor P2Y6 (P2RY6) or the mock plasmid and treated with various concentrations of uridine 5'-diphosphate (UDP). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 96 nM.