CASR

Figure. Concentration-dependent activation of CASR by cinacalcet
Reporter cells were transfected with either the expression plasmid for calcium sensing receptor (CASR) or the mock plasmid and treated with various concentrations of cinacalcet. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 140 nM.
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Symbol
CASR
Nomenclature
calcium sensing receptor
Family
Species
Human