Human GPR183

Figure. Concentration-dependent activation of GPR183 by 7α,25‐dihydroxycholesterol

Reporter cells were transfected with either the expression plasmid for human G protein-coupled receptor 183 (GPR183) or the mock plasmid and treated with various concentrations of 7α,25‐dihydroxycholesterol. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 2.0 nM.

Nomenclature
G protein-coupled receptor 183
Available assay modes
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Panels
à la carte | Hematology | Human non-orphan GPCRs | Immunology/Infection

GPR183 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

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